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Table 1 Characteristics of the women with twin pregnancies in the training and validation sets

From: Development and validation of a prediction model on spontaneous preterm birth in twin pregnancy: a retrospective cohort study

Characteristics

Training set (n = 1313)

Validation set (n = 564)

P value

Age (years), n (%)

  

0.857

 < 35

1081 (82.3)

467 (82.8)

 

 ≥ 35

232 (17.7)

97 (17.2)

 

Pre-pregnancy BMI (kg/m2), n (%)

  

0.575

 Normal

1035 (78.8)

443 (78.5)

 

 Underweight

136 (10.4)

63 (11.2)

 

 Overweight

120 (9.14)

53 (9.40)

 

 Obesity

22 (1.68)

5 (0.89)

 

Nulliparity, n (%)

  

0.277

 No

258 (19.6)

98 (17.4)

 

 Yes

1055 (80.4)

466 (82.6)

 

Chorionicity, n (%)

  

0.460

 Dichorionic diamniotic

1131 (86.1)

496 (87.9)

 

 Monochorionic diamniotic

179 (13.6)

68 (12.1)

 

 Monochorionic monoamniotic

3 (0.23)

0 (0.00)

 

Conception modalities, n (%)

  

0.106

 Spontaneous conception

386 (29.4)

142 (25.2)

 

 IVF

909 (69.2)

417 (73.9)

 

 Ovulation induction

18 (1.37)

5 (0.89)

 

Pre-pregnancy diabetes, n (%)

  

0.935

 No

1252 (95.4)

539 (95.6)

 

 Yes

61 (4.65)

25 (4.43)

 

Gestation diabetes, n (%)

  

0.310

 No

963 (73.3)

427 (75.7)

 

 Yes

350 (26.7)

137 (24.3)

 

Pre-pregnancy hypertension, n (%)

  

0.893

 No

1272 (96.9)

545 (96.6)

 

 Yes

41 (3.12)

19 (3.37)

 

Hypertensive disorders of pregnancy, n (%)

  

0.739

 No

1152 (87.7)

491 (87.1)

 

 Yes

161 (12.3)

73 (12.9)

 

Scarred uterus, n (%)

  

0.554

 No

1220 (92.9)

529 (93.8)

 

 Yes

93 (7.08)

35 (6.21)

 

Infections, n (%)

  

0.620

 No

1195 (91.0)

518 (91.8)

 

 Yes

118 (8.99)

46 (8.16)

 

Cervical incompetence, n (%)

  

0.110

 No

1238 (94.3)

520 (92.2)

 

 Yes

75 (5.71)

44 (7.80)

 

Thyroid abnormalities, n (%)

  

0.869

 No

1176 (89.6)

503 (89.2)

 

 Yes

137 (10.4)

61 (10.8)

 

Anemia, n (%)

  

0.457

 Normal

1002 (76.3)

447 (79.3)

 

 Mild

184 (14.0)

64 (11.3)

 

 Moderate

100 (7.62)

42 (7.45)

 

 Severe

27 (2.06)

11 (1.95)

 

Hypoproteinemia, n (%)

  

0.727

 No

1193 (90.9)

516 (91.5)

 

 Yes

120 (9.14)

48 (8.51)

 

Thrombocytopenia, n (%)

  

0.112

 No

1234 (94.0)

541 (95.9)

 

 Yes

79 (6.02)

23 (4.08)

 
  1. BMI body mass index, IVF in vitro fertilization-embryo transfer