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Table 2 Characteristics of twin pregnancy women with and without sPTB in the training set

From: Development and validation of a prediction model on spontaneous preterm birth in twin pregnancy: a retrospective cohort study

Characteristics

Control (n = 928)

sPTB (n = 385)

P

Age (years), n (%)

  

< 0.001

 < 35

796 (85.8)

285 (74.0)

 

 ≥ 35

132 (14.2)

100 (26.0)

 

Pre-pregnancy BMI (kg/m2), n (%)

  

< 0.001

 Normal

769 (82.9)

266 (69.1)

 

 Underweight

77 (8.30)

59 (15.3)

 

 Overweight

76 (8.19)

44 (11.4)

 

 Obesity

6 (0.65)

16 (4.16)

 

Nulliparity, n (%)

  

0.045

 No

196 (21.1)

62 (16.1)

 

 Yes

732 (78.9)

323 (83.9)

 

Chorionicity, n (%)

  

0.114

 Dichorionic diamniotic

810 (87.3)

321 (83.4)

 

 Monochorionic diamniotic

116 (12.5)

63 (16.4)

 

 Monochorionic monoamniotic

2 (0.22)

1 (0.26)

 

Conception modalities, n (%)

  

0.308

 Spontaneous conception

264 (28.4)

122 (31.7)

 

 IVF

653 (70.4)

256 (66.5)

 

 Ovulation induction

11 (1.19)

7 (1.82)

 

Pre-pregnancy diabetes, n (%)

  

< 0.001

 No

909 (98.0)

343 (89.1)

 

 Yes

19 (2.05)

42 (10.9)

 

Gestation diabetes, n (%)

  

0.694

 No

684 (73.7)

279 (72.5)

 

 Yes

244 (26.3)

106 (27.5)

 

Pre-pregnancy hypertension, n (%)

  

0.001

 No

909 (98.0)

363 (94.3)

 

 Yes

19 (2.05)

22 (5.71)

 

Hypertensive disorders of pregnancy, n (%)

  

0.154

 No

806 (86.9)

346 (89.9)

 

 Yes

122 (13.1)

39 (10.1)

 

Scarred uterus, n (%)

  

0.216

 No

868 (93.5)

352 (91.4)

 

 Yes

60 (6.47)

33 (8.57)

 

Infections, n (%)

  

0.144

 No

852 (91.8)

343 (89.1)

 

 Yes

76 (8.19)

42 (10.9)

 

Cervical incompetence, n (%)

  

< 0.001

 No

900 (97.0)

338 (87.8)

 

 Yes

28 (3.02)

47 (12.2)

 

Thyroid abnormalities, n (%)

  

0.894

 No

830 (89.4)

346 (89.9)

 

 Yes

98 (10.6)

39 (10.1)

 

Anemia, n (%)

  

0.069

 Normal

726 (78.2)

276 (71.7)

 

 Mild

119 (12.8)

65 (16.9)

 

 Moderate

67 (7.22)

33 (8.57)

 

 Severe

16 (1.72)

11 (2.86)

 

Hypoproteinemia, n (%)

  

0.364

 No

848 (91.4)

345 (89.6)

 

 Yes

80 (8.62)

40 (10.4)

 

Thrombocytopenia, n (%)

  

0.234

 No

867 (93.4)

367 (95.3)

 

 Yes

61 (6.57)

18 (4.68)

 
  1. sPTB spontaneous preterm birth, BMI body mass index, IVF in vitro fertilization-embryo transfer