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Table 1 Semen parameters of the patient and normal control

From: A loss-of-function variant in ZCWPW1 causes human male infertility with sperm head defect and high DNA fragmentation

Semen parameters

Patient

Normal control

Normospermic parameters#

Sperm volume (mL)

3.8

4.5

≥ 1.5

PH

7.4

7.4

≥ 7.2

Sperm concentration (million/mL)

8.6

73.8

≥ 15

Total sperm count (million/ejaculate)

32.7

332.1

≥ 39

Progressive motility sperm (%)

18

81

≥ 32

Vitality (%)

82

85

≥ 58

Normal spermatozoa (%)*

1.0

77

≥ 4

Head defect (%)*

99

12

–

Tail defect (%)*

24.9

19.8

–

  1. #Lower and upper reference limits are shown according to the World Health Organization standards (WHO, 2021)
  2. *The calculations were performed including 200 sperm based on the WHO laboratory manual for the examination and processing of human semen