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Table 3 Laboratory and pregnancy outcomes after fresh embryo transfers

From: What is the impact of endometriosis and the AFS stage on cumulative pregnancy rates in IVF programs?

 

Group A

Group B

Group C

Group D

Group E

p

Number of oocyte pick-ups

358

394

50

62

282

 

Total oocytes (n)

8.3 ± 4.4

7.9 ± 4.2

8.8 ± 4.9

7.1 ± 3.3

8.0 ± 4.9

*A–D, C–D

M2 oocytes (n)

6.9 ± 5.3

6.7 ± 5.3

7.9 ± 5.7

6.0 ± 4.1

7.1 ± 5.4

*C–D

2 pronuclei (n)

4.7 ± 3.1

4.4 ± 3.0

5.1 ± 4.3

3.7 ± 2.0

4.5 ± 2.7

*B–D, C–D; **D–E; ***A–D

Fertilization rate (%) (2 PN/M2 ooc)

68.0

65.6

64.5

61.5

63.3

 

Total embryos (n)

3.9 ± 2.9

3.9 ± 3.3

4.8 ± 3.2

2.9 ± 2.4

4.1 + 3.3

**A–D, B–D; ***C–D, D–E

Cleaved/blastocyst (%/%)

40.3/59.7

39.5/60.5

32.0/68.0

51.6/48.4

38.2/61.8

***A–C, A–D, B–D, C–D, D–E

Cleavage rate (%) (emb/M2 ooc)

56.5

58.2

60.7

48.3

57.7

 

Vitrified embryo (n)

2.4 ± 1.3

2.6 ± 1.4

3.1 ± 1.8

1.7 ± 0.9

2.7 ± 1.5

*A–B; **A–C, A–E; ***A–D, B–D, C–D, D–E

N fresh embryo transfers

168

210

24

30

156

 

Day of fresh embryo transfers

 Day 2 or 3 (%)

17.3

16.2

8.4

23.4

7.1

***A–E, B–E, D–E

 Day 5 (%)

82.7

83.8

91.6

76.6

92.9

Embryo/transfer (n)

1.2 ± 0.4

1.3 ± 0.4

1.2 ± 0.4

1.2 ± 0.4

1.3 ± 0.4

 

Clinical pregnancy

48

64

6

4

54

 

EPL (n)

8

10

2

0

8

 

Ectopic pregnancy (n)

0

6

0

0

6

 

Twin pregnancy (n)

4

12

2

2

8

 

CP/c (%)

11.1

13.9

10.7

4.5

17.0

**D–E

CP/opu (%)

13.4

16.2

12.0

6.4

19.1

*D–E

CP/transfer (%)

28.5

30.4

25.0

13.3

34.6

*D–E

IR (%)

24.7

25.6

24.1

13.8

28.5

***A–D, B–D, D–E

Ongoing pregnancy

40

48

4

4

40

 

OP/c (%)

9.3

10.4

7.1

4.5

12.6

*D–E

OP/opu (%)

11.1

12.1

8.0

6.4

14.1

 

OP/transfer (%)

23.8

22.8

16.6

13.3

25.6

 
  1. Group A: women without endometriosis; group B: women with endometriosis (all stages); group C: women with stage 1/2 endometriosis; group D: women with stage 3/4 endometriosis (without endometrioma); group E: women with endometrioma alone
  2. EPL early pregnancy loss, CP clinical pregnancy, OP ongoing pregnancy, c cycle, opu oocytes pick-up, t transfer, IR implantation rate
  3. Statistical analysis: *p < 0.05; **p < 0.01; ***p < 0.001. The other comparisons were not significant