What is the impact of endometriosis and the AFS stage on cumulative pregnancy rates in IVF programs?

Table 4 Frozen/thawed embryo transfer outcomes and cumulative clinical and ongoing pregnancy rates/couple

	Group A	Group B	Group C	Group D	Group E	p
N FET cycles	304	260	44	34	182
N FE transfers	234	236	40	28	168
Day of FE transfers
Day 2 or 3 (%)	26.5	23.8	22.5	32.2	22.1
Day 5 (%)	73.5	76.2	77.5	67.8	77.9
Frozen embryos per transfer	1.1 ± 0.3	1.1 ± 0.3	1.1 ± 0.2	1.2 ± 0.3	1.1 ± 0.3
Clinical pregnancy	38	36	8	4	24
EPL (n)	6	10	0	2	8
Ectopic pregnancy (n)	0	0	0	0	0
Twin pregnancy (n)	0	2	0	2	0
CP/cycle %	12.5	13.8	18.1	11.7	13.1
CP/transfer %	16.2	15.2	20.0	14.2	14.2
IR %	14.7	14.6	18.1	17.6	13.0
OPs	32	26	8	2	16
OP/cycle %	10.5	10.0	18.1	5.8	8.7
OP/transfer %	13.6	11.0	20.0	7.1	9.5
CCPR/couple %	32.5	34.7	38.8	14.8	39.3	**A–D, B–D, C–D, D–E
COPR/couple %	27.2	25.6	33.3	11.1	28.2	D–E; *C–D

Group A: women without endometriosis; group B: women with endometriosis (all stages); group C: women with stage 1/2 endometriosis; group D: women with stage 3/4 endometriosis (without endometrioma); group E: women with endometrioma alone
FET frozen embryo transfer, EPL early pregnancy loss, CP clinical pregnancy, OP ongoing pregnancy, IR implantation rate, CCPR cumulative clinical pregnancy rate, COPR cumulative ongoing pregnancy rate
Statistical significance: *p < 0.05; **p < 0.01. The other comparisons were not significant

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