Skip to main content

Table 3 Research priorities during pregnancy to reduce preterm birth rates and to benefit the preterm baby

From: Born Too Soon: Care during pregnancy and childbirth to reduce preterm deliveries and improve health outcomes of the preterm baby

Description
Epidemiological research to:
• Examine the relationships between maternal risk factors and preterm birth at a population level (e.g., nutritional, infection, age and other socio-demographic factors)
Discovery
Basic science research on normal and abnormal pregnancies to:
• Identify the causal pathways leading to preterm labour and birth
• Understand the gestational clock triggering the onset of labour
• Explore the genetic determinants of preterm birth and genetic-environment interactions increasing risk of preterm birth
Development
Translational research to:
• Develop simple screening tools based on the findings of biological and genetic research for identifying women at high risk of preterm birth and preterm labour
• Develop robust diagnostic tools for universal application (e.g., anaemia, syphilis)
Delivery
Clinical trials and other studies to:
• Build the evidence base on available and promising interventions
• Determine effectiveness of interventions delivered individually and as packages of care
Implementation research to:
• Address coverage gaps by increasing the availability of antenatal care and women's ability to access services around the world
• Address quality of care gaps by increasing the uptake of evidence-based interventions and intervention packages by health care providers (e.g., syphilis testing and screening, blood pressure monitoring during antenatal care visits, etc.)
  1. Source: Born Too Soon report [1].