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Table 4 Thyroid screening, leptin, adiponectin, insulin, C peptide, IGF-1, and hsCRP before and after 4 months with SCI

From: Metabolic effects of the contraceptive skin patch and subdermal contraceptive implant in Mexican women: A prospective study

Variable

Basal

4 months

p

Reference values

TSH (μU/ml)

2.0 (0.4-5.7)

1.6 (0.4-5.5)

0.034

0.34-5.60

T4 (μg/dl)

8.1 (4.2-11.7)

8.6 (6.3-12.7)

0.120

6.09-12.23

T3 (ng/dl)

120.6 (79.2-208.4)

123.1 (92.6-173.4)

0.622

75.0-250.0

FTI

7.8 (3.9-12.1)

8.3 (6.1-13.4)

0.367

4.5-15.0

PBI (μg/dl)

5.2 (2.7-7.6)

5.6 (4.1-8.2)

0.117

3.90-7.80

TU (%)

0.9 (0.9-1.0)

0.9 (0.8-1.0)

0.974

0.75-1.25

Anti-Tg (μU/ml)

15.8 (5.0-103.4)

14.2 (5.0-86.2)

0.625

5-100

Anti-TPO (μU/ml)

1.5 (0.3-59.0)

1.4 (0.3-43.0)

0.052

0-9

Insulin (μU/ml)

13.0 (4.5-43.1)

11.2 (3.7-26.8)

0.449

5-30

C peptide (ng/ml)

3.1 (1.3-7.4)

3.4 (1.8-5.8)

0.128

0.5-3.0

IGF-1 C (pg/ml)

251.2 (76.5-486.4)

279.7 (119.1-593.5)

0.016

115.0-307

Leptin (ng/ml)

9.1 (1.5-50.3)

11.1 (1.0-32.8)

0.812

4.1-22.4

Adiponectin (μg/ml)

16.0 (8.9-29.9)

14.7 (9.0-26.2)

0.837

3.9-25.6

hsCRP (mg/dl)

0.26 (0.02-1.2)

0.25 (0.03-1.0)

0.837

0.0-0.8

  1. Results are expressed as median (percentiles: 2.5-97.5). Significant p values are shown in bold. All variables had an abnormal distribution (p < 0.050). TSH: thyroid-stimulating hormone; T4: total thyroxine; T3: total triiodothyronine; FTI: free thyroxine index; PBI: serum protein-bound iodine; TU: thyroid uptake; anti-Tg: anti-thyroglobulin antibodies; anti-TPO: anti-thyroid microsomal antibodies; IGF-1: insulin growth factor-1; hsCRP: high-sensitivity C-reactive protein. Kolmogorov Smirnov test was used to establishing the distribution of variables. Mann–Whitney U test and Wilcoxon test were used in order to analyze non-parametric values. Student t test and paired t tests were used for parametric variables.