|
Variable
|
Basal
|
4 months
|
p
|
Reference values
|
|---|
|
TSH (μU/ml)
|
2.4 (0.8-6.2)
|
1.9 (0.7-3.9)
|
0.158
|
0.34-5.60
|
|
T4 (μg/dl)
|
8.5 (6.1-11.5)
|
9.2 (7.0-11.4)
|
0.072
|
6.09-12.23
|
|
T3 (ng/dl)
|
124.2 (68.1-188.3)
|
148.2 (110.0-220.2)
|
0.001
|
75-250
|
|
FTI
|
8.2 (5.7-11.9)
|
8.3 (6.9-10.0)
|
0.864
|
4.5-15.0
|
|
PBI (μg/dl)
|
5.5 (4.0-7.5)
|
6.0 (4.6-7.4)
|
0.070
|
3.90-7.80
|
|
TU (%)
|
1.0 (0.8-1.2)
|
0.8 (0.8-1.0)
|
0.009
|
0.75-1.25
|
|
Anti-Tg (μU/ml)
|
8.1 (5.0-333.1)
|
7.1 (5.1-230.4)
|
0.159
|
5-100
|
|
Anti-TPO (μU/ml)
|
0.7 (0.3-404.7)
|
0.7 (0.3-378.3)
|
0.915
|
0-9
|
|
Insulin (μU/ml)
|
8.7 (3.8-33.2)
|
9.2 (4.7-19.5)
|
0.547
|
5-30
|
|
C peptide (ng/ml)
|
2.7 (1.6-5.7)
|
2.8 (1.8- 4.2)
|
0.559
|
0.5-3.0
|
|
IGF-1 C (pg/ml)
|
227.0 (89.3-499.0)
|
225.4 (16.9-369.3)
|
0.775
|
115-307
|
|
Leptin (ng/ml)
|
9.5 (1.9-24.2)
|
8.9 (3.8-30.0)
|
0.090
|
4.1-22.4
|
|
Adiponectin (μg/ml)
|
16.6 (6.5-41.8)
|
17.9 (5.2-32.1)
|
0.409
|
3.9-25.6
|
|
hsCRP (mg/dl)
|
0.28 (0.01-1.0)
|
0.51 (0.1-1.3)
|
0.013
|
0.0-0.8
|
- Results are expressed as median (percentiles: 2.5-97.5). Significant p values are shown in bold. With the exception of total thyroxine (T4; p = 0.373), thyroid uptake (TU; p = 0.748) and serum protein-bound iodine (PBI; p = 0.594), all variables had an abnormal distribution (p < 0.050). TSH: thyroid-stimulating hormone; T3: total triiodothyronine; FTI: free thyroxine index; anti-Tg: anti-thyroglobulin antibodies; anti-TPO: anti-thyroid microsomal antibodies; IGF-1: insulin growth factor-1; hsCRP: high-sensitivity C-reactive protein (hsCRP). Kolmogorov Smirnov test was used to establishing the distribution of variables. Mann-Whitney U test and Wilcoxon test were used to analyze non-parametric values. Student t test and paired t tests were used for parametric variables.
