|
Variables
|
PCOS (n = 263)
|
A (n = 139)
|
B (n = 10)
|
C (n = 36)
|
D (n = 78)
|
Control (n = 263)
|
P-value PCOS phenotypes vs controls
|
|---|
|
Fasting insulin ≥20 μU/mL
|
64 (24.3)
|
33 (23.7)
|
4 (40)
|
10 (27.8)
|
17(21.8)
|
17 (6.5)
|
<0.001
|
|
Fasting glucose/Fasting insulin ≤4.5
|
61 (23.2)
|
32 (23)
|
4 (40)
|
10 (27.8)
|
15(19.2)
|
17 (6.5)
|
< 0.001
|
|
HOMA-IR ≥ 3.8
|
90 (34.2)
|
49 (35.3)
|
5 (50)
|
12 (33.3)
|
24(30.8)
|
36 (13.7)
|
< 0.001
|
|
Ratio 2-h glucose/2-h insulin ≤1
|
61 (23.2)
|
40 (28.8)
|
3 (30)
|
9 (25)
|
9 (11.5)
|
13(4.9)
|
< 0.001
|
|
Normal GTT
|
176 (66.9)
|
88 (63.3)
|
5 (50)
|
26 (72.2)
|
57(73.1)
|
196(74.5)
|
0.092
|
|
Prediabetes (IFG and/or IGT)
|
75 (28.5)
|
46 (33.1)
|
5 (50)
|
8 (22.2)
|
16(20.5)
|
61(23.2)
|
|
Type 2 diabetes mellitus
|
12 (4.6)
|
5 (3.6)
|
0 (0)
|
2 (5.6)
|
5 (6.4)
|
6 (2.3)
|
|
Insulin resistance (IR)
|
112 (42.6)
|
64 (46)*
|
5 (50)*
|
17(47.2)*
|
26(33.3)*
|
45(17.1)
|
<0.001
|
|
Metabolic syndrome (MetS)
|
141 (53.6)
|
81 (58.3)**
|
8(80)**
|
17(47.2)**
|
35(44.9)**
|
86(32.7)
|
<0.001
|
|
Family history of T2DM
|
131 (49.8)
|
65 (46.8)+
|
4 (40)+
|
18 (50)+
|
44(56.4)+
|
104 (39.5)
|
0.094
|
- Data are shown as n (%). P-values were calculated using Chi-square test.
- *Insulin resistance frequencies did not differ significantly between the PCOS phenotypes (P = 0.271).
- **Metabolic syndrome frequencies did not differ significantly between phenotypes (P = 0.069).
- +Family history of T2DM frequencies did not differ significantly between phenotypes (P = 0.525).
- (Note: (i) Phenotype A (O + H + P), (ii) Phenotype B (O + H), (iii) Phenotype C (H + P) and (iv) Phenotype D (O + P). IFG: impaired fasting glucose, IGT: impaired glucose tolerance.
