Organ system-based | Markers |
---|---|
Cardiac dysfunction | Pulmonary oedema Cardiac arrest |
Vascular dysfunction | Hypovolaemia requiring ≥ 5 units of blood products |
Immunological dysfunction | ICU admission for sepsis Emergency hysterectomy for sepsis |
Respiratory dysfunction | Intubation and ventilation for any reason other than general anaesthesia Oxygen saturation of less than 90% for more than 60 min The ratio of the partial pressure of oxygen in arterial blood to the percentage oxygen in inspired air is ≤ 3 (paO2/FiO2 ≤ 3) |
Renal dysfunction | Oliguria, ≤ 400 ml/24 hr that does not respond to careful fluid replacement or attempts at inducing with dopamine or infusion Acute deterioration in urea > 15 mmol/l or of creatinine to > 400 mmol/l |
Liver dysfunction | Jaundice in the presence of pre-eclampsia |
Metabolic dysfunction | Diabetic keto-acidosis |
Coagulation dysfunction | Acute thrombocytopenia requiring a platelet transfusion |
Cerebral dysfunction | Coma lasting > 12 hours Subarachnoid or intracerebral haemorrhage |