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Table 3 Ovarian stimulation results in the P2 and P3 COH protocols

From: Comparative prospective study of 2 ovarian stimulation protocols in poor responders: effect on implantation rate and ongoing pregnancy

 

P2

P3

Number of cycles

220

220

Total FSH/hMG dose (IU)

4664 ± 605

4680 ± 641

Duration of stimulation (days)

11.8 ± 2.3

11.6 ± 2.7

Estradiol levels on hCG day (pg/ml)

1215 ± 350a

712 ± 251b

Progesterone levels on hCG day (ng/ml)

0.8 ± 0.2

0.7 ± 0.3

Endometrial thickness (mm)

8.7 ± 1.3

8.4 ± 1.2

No of oocyte pick-ups

204

196

No of oocytes retrieved (per pick-up)

1224 (6.0 ± 4.1)

1218 (6.2 ± 4.9)

No of M2 oocytes retrieved

894 (4.3 ± 3.7)

913 (4.6 ± 4.1)

No of oocytes fertilized

721

694

No of embryos obtained

487 (2.3 ± 0.5)a

426 (2.1 ± 0.3)b

Grade I/II embryos (%)

35.9

36.8

No of overall cancelled cycles (%)

42 (19.0)

51 (23.1)

No of embryos transfer

178

169

Embryos per transfer

2.1 ± 0.2c

1.9 ± 0.4d

Clinical pregnancy rate per transfer (%)

17.9

15.9

Ongoing pregnancy rate per transfer (%)

14.6

14.2

Implantation rate per embryo transferred (%)

8.9

8.4

No of cycles with cryopreservation (%)

15.7

9.4

No of cryopreserved embryos

69

43

  1. a-b: significant difference at p < 0.001
  2. c-d: p < 0.01