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Table 3 Ovarian stimulation results in the P2 and P3 COH protocols

From: Comparative prospective study of 2 ovarian stimulation protocols in poor responders: effect on implantation rate and ongoing pregnancy

  P2 P3
Number of cycles 220 220
Total FSH/hMG dose (IU) 4664 ± 605 4680 ± 641
Duration of stimulation (days) 11.8 ± 2.3 11.6 ± 2.7
Estradiol levels on hCG day (pg/ml) 1215 ± 350a 712 ± 251b
Progesterone levels on hCG day (ng/ml) 0.8 ± 0.2 0.7 ± 0.3
Endometrial thickness (mm) 8.7 ± 1.3 8.4 ± 1.2
No of oocyte pick-ups 204 196
No of oocytes retrieved (per pick-up) 1224 (6.0 ± 4.1) 1218 (6.2 ± 4.9)
No of M2 oocytes retrieved 894 (4.3 ± 3.7) 913 (4.6 ± 4.1)
No of oocytes fertilized 721 694
No of embryos obtained 487 (2.3 ± 0.5)a 426 (2.1 ± 0.3)b
Grade I/II embryos (%) 35.9 36.8
No of overall cancelled cycles (%) 42 (19.0) 51 (23.1)
No of embryos transfer 178 169
Embryos per transfer 2.1 ± 0.2c 1.9 ± 0.4d
Clinical pregnancy rate per transfer (%) 17.9 15.9
Ongoing pregnancy rate per transfer (%) 14.6 14.2
Implantation rate per embryo transferred (%) 8.9 8.4
No of cycles with cryopreservation (%) 15.7 9.4
No of cryopreserved embryos 69 43
  1. a-b: significant difference at p < 0.001
  2. c-d: p < 0.01