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Table 1 Clinical and biochemical parameters of smokers stratified by the number of sticks smoked per day

From: Tobacco smoking is associated with decreased semen quality

Parameters

Non-smokers (N = 45)

Mild (N = 30)

Moderate (N = 30)

Heavy (N = 35)

p-value

Age (years)

35.0 ± 5.4

35.0 ± 7.4

37.3 ± 7.4

37.6 ± 9.3

0.847

Volume (ml)

3.37 ± 1.0

2.7 ± 0.7a

2.2 ± 0.4b

2.6 ± 0.3c

0.028*

pH

7.70 ± 0.2

7.70 ± 0.3

7.60 ± 0.8

6.80 ± 1.5

0.736

Immobile (%)

7.64 ± 2.3

35.1 ± 9.8a

36.2 ± 8.7b

34.5 ± 10.1c

0.012*

Active (%)

53.76 ± 12.4

48.3 ± 11.7

41.4 ± 13.7b

24.9 ± 9.5c, d

0.034*

Sluggish (%)

10.36 ± 4.5

16.6 ± 6.7a

16.0 ± 5.5b

19.6 ± 7.6c

0.043*

Viability (%)

65.0 ± 14.8

65.1 ± 13.1

60.3 ± 15.7

46.8 ± 17.2c, d

0.284

Morphology (%)

48.40 ± 12.1

43.8 ± 9.5

38.8 ± 10.2b

26.1 ± 10.4c, d

0.038*

Count (sperm/ml)

93.17 ± 22.1

73.6 ± 21.6a

64.3 ± 19.8b

24.5 ± 12.1c

0.041*

PC(cells/HPF)

5.7 ± 1.2

6.9 ± 2.1a

6.2 ± 1.8

6.2 ± 2.7

0.436

EC (cells/HPF)

2.0 ± 0.9

2.4 ± 1.1

2.1 ± 0.8

2.4 ± 0.7

0.865

RBC (cells/HPC)

0.08 ± 0.0

0.1 ± 0.0

0.1 ± 0.0

0.1 ± 0.0

0.973

FSH (IU/L)

8.56 ± 2.8

6.90 ± 2.6a

6.80 ± 2.7b

5.80 ± 2.1c

0.007*

LH (IU/L)

6.24 ± 1.9

6.10 ± 2.4

6.00 ± 1.9

5.60 ± 1.2c

0.439

TT (nmol/L)

18.8 ± 4.6

14.9 ± 3.2

14.5 ± 5.7

13.8 ± 5.6

0.039*

FT (nmol/L)

0.36 ± 0.1

0.27 ± 0.1a

0.26 ± 0.1b

0.24 ± 0.1c

0.021*

Bio T (nmol/L)

8.43 ± 2.9

6.21 ± 2.2a

5.82 ± 2.0b

5.50 ± 1.4c

0.018*

SHBG (nmol/L)

39.6 ± 7.3

41.8 ± 11.6

42.4 ± 5.0

43.2 ± 9.3

0.389

E2 (pg/ml)

23.0 ± 9.2

24.5 ± 9.5

25.3 ± 10.1

25.9 ± 10.8

0.691

PROL (ng/ml)

15.0 ± 3.6

15.1 ± 4.4

16.8 ± 2.8

17.3 ± 3.1

0.352

  1. The results for the clinical and biochemical parameters of the study population
  2. Values are given as mean ± standard deviation. *mean difference is significant (p <0.05). PC pus cells, EC epithelial cells, RBC red blood cells, FSH follicle stimulation hormone, LH luteinizing hormone, TT total testosterone, FT free testosterone, Bio T bioavailable testosterone, SHBG sex hormone binding globulin, E2 estradiol and PROL is prolactin. a p <0.05for corresponding values of mild smokers with controls; b p <0.05 for comparison of moderate smokers with controls; c p <0.05 for corresponding values of heavy smokers with non-smokers; d p <0.05 for corresponding values of heavy smokers with mild smokers