Primary outcome | |
Weight in kilograms | |
Secondary outcomes | |
(1) reproductive outcomes: | a) cycle duration and frequency |
b) spontaneous pregnancies | |
2) anthropomorphometric outcomes: | a) BMI |
b) waist circumference (WC) | |
c) hip circumference (HC) | |
d)WC/HC ratio | |
(3) clinical and biochemical PCOS features: | a) hair growth pattern |
- Ferriman Gallwey score | |
b) blood pressure | |
c) transvaginal ultrasound outcomes | |
- ovarian volume | |
- follicle count | |
- total follicles per ovary | |
d) endocrine outcomes | |
- insulin resistance | |
- hyperandrogenism | |
- dyslipidemia | |
(4) psychological outcomes: | a) eating behaviour and disturbances |
- The Dutch Eating Behaviour Questionnaire (NVE) | |
- Eating Disorder Examination Questionnaire (EDE-Q) | |
b) quality of Life | |
- Short Form 36 (SF-36) | |
- Polycystic Ovary Syndrome Questionnaire (PCOSQ) | |
c) depression | |
- Beck Depression Inventory (BDI) | |
d) self-esteem | |
- Rosenberg Self Esteem Scale (RSE) | |
e) fear of negative appearance | |
- Fear of Negative Appearance Evaluation Scale (FNAES) | |
f) satisfaction | |
- Self-constructed questionnaire | |
(5) physical activity: | a) perceived level of daily physical activity |
- the International Physical Activity Questionnaire (IPAQ) | |
b) the intervention group: submaximal bicycle test | |
(5) physical activity: | a) food intake |
-energy (calories) | |
- protein | |
- fat | |
- saturated fat | |
- carbohydrates | |
- mono- and disaccharides | |
- drinks (ml) | |
(7) other: | - attendance at meetings |
- drop-out and reasons for drop-out |