Adverse perinatal outcomes | WHOGS | WHOMCS | Combined | ||||||
---|---|---|---|---|---|---|---|---|---|
n/N (%) | Crude ORa (95% CI) | AORb (95% CI) | n/N (%) | Crude ORa (95% CI) | AORb (95% CI) | n/N (%) | Crude ORa (95% CI) | AORb (95% CI) | |
APGAR <7 at 5 min | |||||||||
IOL | 40/2119 (1.9) | 1 | 1 | 23/2213 (1.1) | 1 | 1 | 63/4332 (1.5) | 1 | 1 |
ECS | 3/691 (0.4) | 0.39 (0.12, 1.22) | 0.31 (0.08, 1.23) | 13/1260 (1.0) | 1.20(0.61, 2.36) | 0.92 (0.45, 1.90) | 16/1951 (0.8) | 0.81 (0.47, 1.40) | 0.67 (0.36, 1.23) |
EM | 309/13338 (2.3) | 1.10 (0.77, 1.57) | 1.21 (0.82, 1.81) | 232/13382 (1.8) | 1.41 (0.91, 2.20) | 1.39 (0.88, 2.19) | 541/26720 (2.0) | 1.19 (0.90, 1.57) | 1.27 (0.95, 1.72) |
Admission to NICU | |||||||||
IOL | 146/2119 (6.9) | 1 | 1 | 101/2213 (4.6) | 1 | 1 | 247/4332 (5.7) | 1 | 1 |
ECS | 67/691 (9.7) | 1.61 (1.15, 2.26) | 1.13 (0.75, 1.72) | 117 /1260 (9.3) | 1.99 (1.47, 2.71) | 1.76 (1.28, 2.42) | 184/1951 (9.4) | 1.85 (1.49, 2.31) | 1.51 (1.19, 1.92) |
EM | 1035/13338 (7.8) | 0.94 (0.76, 1.15) | 0.99 (0.79, 1.26) | 587/13382 (4.4) | 0.90 (0.71, 1.15) | 0.92 (0.72, 1.18) | 1622/26720 (6.1) | 0.93 (0.80, 1.08) | 0.95 (0.81, 1.12) |
Stillbirth | |||||||||
IOL | 10/2119 (0.5) | 1 | 1 | 8/2213 (0.4) | 1 | 1 | 18/4332 (0.4) | 1 | 1 |
ECS | 0/691 (0.0) | – | – | 4 /1260 (0.3) | 1.06 (0.31, 3.62) | 0.99 (0.27, 3.57) | 4/1951 (0.2) | 0.70 (0.24, 1.99) | 0.61 (0.20, 1.83) |
EM | 47/13338 (0.4) | 0.69 (0.33, 1.46) | 0.63 (0.29, 1.38) | 73/13382 (0.6) | 1.29 (0.60, 2.78) | 1.29 (0.56, 2.98) | 120/26720 (0.5) | 0.97 (0.58, 1.60) | 0.92 (0.54, 1.58) |
Early neonatal death | |||||||||
IOL | 2/2119 (0.1) | 1 | 1 | 7/2213 (0.3) | 1 | 1 | 9/4332 (0.2) | 1 | 1 |
ECS | 1/691 (0.1) | 2.25 (0.20, 25.5) | 2.10 (0.18, 24.7) | 4 /1260 (0.3) | 1.23 (0.35, 4.35) | 0.95 (0.26, 3.45) | 5/1951 (0.2) | 1.69 (0.59, 4.85) | 1.35 (0.46, 4.00) |
EM | 50/13338 (0.4) | 4.17 (0.99, 17.5) | 3.82 (0.89, 16.2) | 67/13382 (0.5) | 1.28 (0.57, 2.91) | 1.11 (0.48, 2.56) | 117/26720 (0.4) | 1.94 (0.99, 3.80) | 1.74 (0.88, 3.45) |
Perinatal death | |||||||||
IOL | 12/2119 (0.6) | 1 | 1 | 15/2213 (0.7) | 1 | 1 | 27/4332 (0.6) | 1 | 1 |
ECS | 1/691 (0.1) | 0.42 (0.06, 3.02) | 0.41 (0.05, 3.10) | 8 /1260 (0.6) | 1.15 (0.50, 2.66) | 0.96 (0.40, 2.30) | 9/1951 (0.5) | 1.06 (0.50, 2.22) | 0.90 (0.42, 1.94) |
EM | 97/13338 (0.7) | 1.27 (0.68, 2.36) | 1.18 (0.62, 2.22) | 139/13382 (1.0) | 1.20 (0.70, 2.05) | 1.14 (0.65, 2.02) | 236/26720 (0.9) | 1.26 (0.83, 1.89) | 1.19 (0.77, 1.82) |