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Table 2 Summary of candidate predictors (Adapted from Barton and Sibai [35], Edwards 2015 [25], Albright et al. [36])

From: The global maternal sepsis study and awareness campaign (GLOSS): study protocol

Maternal clinical findings  
• Fever
• Temperature instability (core body temperature higher than 38.0 °C or lower than 36.0 °C)
• Tachycardia (heart rate greater than 110 beats/min)
• Tachypnoea (respiratory rate greater than 24 beats/min)
• O2 saturation, PaO2/FiO2
• Diaphoresis
• Nausea or vomiting
• Hypotension or shock
• Oliguria or anuria
• Pain (location based on site of infection)
• Altered mental state (confusion, decreased alertness, Glasgow Coma Scale score)
• Decrease capillarity refill, clammy or mottled skin
• Fetal distress (fetal tachycardia, acidosis)
Maternal Laboratory Findings  
• Leucocytosis or leukopenia, immature neutrophils
• Positive culture from infection site or blood
• Hypoxemia
• Thrombocytopenia, INR, PTT
• Metabolic acidosis
• Hypoperfusion, increased serum lactate
• Low arterial pH
• Increased base deficit
• Elevated serum creatinine
• Elevated liver enzymes, bilirubin
• Serum urea
• Serum sodium
• Serum potassium
• Hyperglycaemia in the absence of diabetes
• Disseminated intravascular coagulation