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Table 1 Adrian Grant’s methodological innovations

From: Features of randomised trials designed by the NPEU Perinatal Trials Service during Adrian Grant’s directorship

• Identification and prioritisation of important questions

• Systematic reviews

• Alliance of patients, carers, and clinicians

• Efficient trial conduct

• Secure randomisation

• Appropriate design, outcomes, and size

• Support for participants

• Newsletters

• Integral economic evaluation

• Embedded methodological research

• Long term follow up

• Feedback of trial results