From: Vitamin D and assisted reproductive treatment outcome: a prospective cohort study
Vitamin D Category | p-value | |||
---|---|---|---|---|
 | Deficienta (< 50 nmol/L) N = 266 | Insufficienta (50-75 nmol/L) N = 154 | Repletea (> 75 nmol/L) N = 80 | |
Age -years(SD) | 33.2 (4.9) | 33.7 (4.4) | 34.2 (4.6) | 0.20 |
BMI (SD) | 24.7 (4.0) | 25.1 (3.6) | 24.1 (3.1) | 0.18 |
Ethnicity (%) | ||||
 White | 93 (36.0) | 101 (39.2) | 64 (24.8) | < 0.001+ |
 South Asian | 125 (71.8) | 37 (21.3) | 12 (6.9) | |
 Black | 20 (66.7) | 8 (26.7) | 2 (6.6) | |
 Chinese | 5 (62.5) | 2 (25.0) | 1 (12.5) | |
 Other | 23 (76.7) | 6 (20.0) | 1 (3.3) | |
Season (%) | ||||
 Winter | 76 (59.4) | 41 (32.0) | 11 (8.6) | < 0.001+ |
 Spring | 77 (61.6) | 39 (31.2) | 9 (7.2) | |
 Summer | 31 (31.0) | 40 (40.0) | 29 (29.0) | |
 Autumn | 82 (55.8) | 34 (23.1) | 31 (21.1) | |
Smoking (%) | ||||
 Smokers | 16 (6.0) | 6 (3.9) | 4 (5.0) | 0.64+ |
Duration of infertility in months (Median-IQR) | 48 (36–72) | 36 (24–60) | 36 (24–60) | 0.04 |
Mean pituitary FSH (iU/ml) (SD) | 7.9 (2.9) | 7.6 (2.9) | 7.9 (4.0) | 0.73 |
Mean AMH (SD) | 18.7 (21.7) | 22.6 (27.4) | 14.3 (14.1) | 0.34 |
Previous live birth (%) | 198 (80.5) | 11 (78.7) | 62 (80.5) | 0.91+ |
Treatment type (%) | ||||
 IVF | 99 (40.2) | 54 (38.3) | 40 (52.0) | 0.37+ |
 ICSI | 130 (52.9) | 78 (55.3) | 33 (42.9) | |
 FET | 17 (6.9) | 9 (6.4) | 4 (5.1) | |
Number of embryos transferred at day 5 post oocyte retrieval (%) | 97 (46.6) | 65 (53.3) | 40 (56.3) | 0.28+ |
Number of embryos transferred (%) | ||||
 Single | 153 (73.6) | 79 (64.8) | 51 (71.8) | 0.23+ |
 Double | 55 (26.4) | 43 (35.2) | 20 (28.2) | |
Top grade embryo transfer | 169 (81.2) | 93 (76.2) | 56 (78.9) | 0.55+ |