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Table 5 Risk of Adverse Neonatal Outcomes Associated with IDIa

From: The relationship between birth intervals and adverse maternal and neonatal outcomes in six low and lower-middle income countries

 

IDI (months)b

Adjusted RR (95% CI)c

6–17

N (%)

18–36

N (%)

37–60

N (%)

61–180

N (%)

6–17 vs. 18–36

37–60 vs. 18–36

61–180 vs. 18–36

Deliveries, N

17,392

91,670

50,447

22,273

   

LBW (<  2500 g)

3705 (21.4)

12,643 (13.8)

5941 (11.8)

2864 (12.9)

1.38 (1.32, 1.44)

1.02 (0.99, 1.05)

1.22 (1.17, 1.27)

VLBW (<  1500 g)

572 (3.3)

1128 (1.2)

567 (1.1)

296 (1.3)

2.35 (2.10, 2.62)

1.10 (1.01, 1.21)

1.47 (1.32, 1.64)

Preterm

3934 (22.7)

13,067 (14.3)

6403 (12.8)

2789 (12.6)

1.44 (1.39, 1.50)

0.97 (0.94, 1.00)

1.06 (1.02, 1.10)

Congenital anomalies

36 (0.2)

166 (0.2)

94 (0.2)

42 (0.2)

1.08 (0.78, 1.50)

1.13 (0.88, 1.45)

1.11 (0.78, 1.59)

Neonatal hospitalization

378 (2.5)

1518 (1.9)

742 (1.7)

470 (2.4)

1.24 (1.11, 1.38)

1.02 (0.94, 1.12)

1.28 (1.15, 1.43)

Stillbirth,

N (Rate/1000)

792 (45.6)

2219 (24.2)

1246 (24.7)

644 (28.9)

1.70 (1.56, 1.86)

1.14 (1.08, 1.22)

1.50 (1.38, 1.62)

Neonatal death < 28 days,

N (Rate/1000)

731 (44.1)

1848 (20.7)

929 (18.9)

456 (21.1)

1.89 (1.74, 2.05)

1.04 (0.97, 1.13)

1.25 (1.14, 1.38)

  1. aFetal/Neonatal outcomes are calculated at the maternal level if at least one fetus/neonate has the outcome
  2. bColumns present N (%) for each adverse delivery outcome within each IDI category, with the exception of stillbirth and neonatal death < 28 days which are presented as rate/1000 deliveries
  3. cRelative risks and 95% confidence intervals from a logistic model with generalized estimating equations to account for the correlation of outcomes within cluster adjusting for maternal age, maternal education, parity, ANC visits, and iron supplements. Very low birthweight (< 1500) and Stillbirth outcomes used a Poisson distribution, all other Fetal/Neonatal outcomes used a Binomial distribution