Endpoints | Sublingual misoprostol (n = 98) | Vaginal misoprostol (n = 100) | RR | 95% CI | p-value | ||
---|---|---|---|---|---|---|---|
n | % | n | % | ||||
Tachysystole (> 6 contractions in 10 min) | 1 | 1 | 12 | 12 | 0.15 | 0.02–0.97 | 0.002** |
Change in cervix after 12 h | 58 | 59.2 | 52 | 52.0 | 1.16 | 0.87–1.55 | 0.31** |
Change in cervix after 24 h | 73 | 74.5 | 74 | 74.0 | 1.01 | 0.73–1.40 | 0.94** |
Failure to achieve vaginal delivery within 12 h | 90 | 91.8 | 93 | 93.0 | 0.92 | 0.56–1.51 | 0.76** |
Failure to achieve vaginal delivery within 24 h | 70 | 71.4 | 66 | 66.0 | 1.14 | 0.83–1.57 | 0.41** |
Need for oxytocin | 33 | 33.7 | 24 | 24.0 | 1.25 | 0.94–1.67 | 0.13** |
Epidural anesthesia | 2 | 2.0 | 1 | 1.0 | 1.35 | 0.60–3.05 | 0.98* |
Maternal preference for sublingual route | 65 | 66.3 | 54 | 54.0 | 1.31 | 0.96–1.78 | 0.08** |
Nausea | 5 | 5.1 | 9 | 9.0 | 0.71 | 0.34–1.45 | 0.28** |
Vomiting | 2 | 2.0 | 2 | 2.0 | 1.01 | 0.37–2.72 | 1.00* |
Diarrhea | 1 | 1.0 | 2 | 2.0 | 0.67 | 0.13–3.34 | 1.00* |
Caesarean section | 56 | 57.1 | 56 | 56.0 | 1.02 | 0.77–1.36 | 0.87** |
Meconium | 6 | 6.1 | 11 | 11.0 | 0.69 | 0.36–1.34 | 0.22** |
Admission to neonatal intensive care unit | 1 | 1.0 | 1 | 1.0 | 1.01 | 0.25–4.07 | 1.00* |
Neonatal resuscitation | 4 | 4.1 | 2 | 2.0 | 1.36 | 0.76–2.44 | 0.66* |