Fig. 4
From: Association of endothelial nitric oxide synthase gene variants with preeclampsia
Structural changes upon Glu298Asp substitution in eNOS protein. a eNOSWT protein, b eNOSMT with red colored tube represent the magnitude of fluctuation and deformation upon mutation. Amino acids colored according to the vibrational entropy change upon mutation. blue represents a rigidification of the structure and red a gain in flexibility (c) shows the atomic representation of substitution of Glu to Asp amino acid substituent indicated in cyan color. c Plot showing deformities in protein upon mutation