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Table 2 Infertility characteristics and pregnancy outcomes in the Mayo Primary Infertility Cohort

From: Fertility trends and comparisons in a historical cohort of US women with primary infertility

Characteristic

Total (N = 1001)

Length of infertility (months)

 No. available

960

 Median (IQR)

16 (12, 24)

Type of Infertility†

 Ovulatory Dysfunction

316 (31.6%)

 Amenorrhea

22

 Oligo-ovulation

239

 PCOS

41

 Hypothalamic hypogonadism

10

 Diminished ovarian reserve

9

 Male factor

246 (24.6%)

 Absence of a male partner

14

 Abnormal semen parameters

231

 Tubal factor

62 (6.2%)

 Uterine

29 (2.9%)

 Endometriosis

104 (10.4%)

 Unexplained

374 (37.4%)

Fertility medications used prior to documented pregnancy‡

 Clomiphene

  No

413 (41.3%)

  < 1 year use

529 (52.8%)

  > 1 year use

59 (5.9%)

 Gonadotropin

  No

792 (79.1%)

  < 1 year use

201 (20.1%)

  > 1 year use

8 (0.8%)

 Letrozole

0 (0%)

 IVF

168 (16.8%)

Ever pregnant

 No

297 (29.7%)

 Yes, with fertility medications to achieve first pregnancy

422 (42.2%)

 Yes, without fertility medications to achieve first pregnancy

282 (28.2%)

  1. †Among the 1001 women and considering the six listed types of infertility, 883 had a single type of infertility, 107 had two of the types, 10 had three types and 1 had 4 types
  2. ‡Among the 1001 women, 353 used none of the four listed fertility medications, 406 used one option, 167 used two options and 75 used three options