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Fig. 2 | Reproductive Health

Fig. 2

From: Altered gene expression of VEGF, IGFs and H19 lncRNA and epigenetic profile of H19-DMR region in endometrial tissues of women with endometriosis

Fig. 2

DNA methylation profile of H19-DMR regulatory regions by chromatin immunoprecipitation (ChIP) assay. A The regions amplified by qPCR are shown by arrows, and nucleotide numbers are relative to the transcription start site. Different letters indicate significant differences between the groups (p < 0.05). Incorporation of MeCP2 on the regulatory regions of B region I, C region II in endometriosis and control groups. The data showed significant hypo-methylation in region II in eutopic group compared to control group. There was no significant difference in the incorporation of MeCP2 in region I between the eutopic, ectopic and control samples. The results are expressed relative to a 1/100 dilution of input chromatin (mean ± SEM)

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