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Table 4 Association between pre-pregnancy BMI or GWG and anogenital distance (AGD) in newborns in stratified analyses

From: Association of pre-pregnancy body mass index and gestational weight gain with neonatal anogenital distance in a Chinese birth cohort

  

Anogenital Distance (mm)

Joint Effect Group

N

unadjusted β (95%CI)

adjusted β (95%CI)a, b

AGDAP in boys

   

 Normal pre-pregnancy BMI with normal GWG

86

Ref.

Ref.

 Normal pre-pregnancy BMI with inadequate GWG

56

− 2.26 (− 3.84, − 0.67)*

− 2.64 (− 4.59, − 0.69)*

 Normal pre-pregnancy BMI with excessive GWG

48

− 1.05 (− 2.71, 0.61)

− 2.65 (− 4.66, − 0.64)*

 Pre-pregnancy underweight with normal GWG

26

− 1.37 (− 3.44, 0.69)

− 1.39 (− 3.88, 1.11)

 Pre-pregnancy overweight or obesity with normal GWG

14

1.40 (− 1.26, 4.06)

0.90 (− 2.66, 4.46)

AGDAS in boys

   

 Normal pre-pregnancy BMI with normal GWG

86

Ref.

Ref.

 Normal pre-pregnancy BMI with inadequate GWG4

56

− 1.71 (− 3.18, − 0.24)*

− 1.58 (− 3.46, 0.30)

 Normal pre-pregnancy BMI with excessive GWG 6

48

0.33 (− 1.22, 1.87)

− 0.17 (− 2.10, 1.77)

 Pre-pregnancy underweight with normal GWG 2

26

0.37 (− 1.54, 2.29)

1.47 (− 0.93, 3.87)

 Pre-pregnancy overweight or obesity with normal GWG 8

14

0.08 (− 2.39, 2.55)

− 0.42 (− 3.85, 3.01)

AGDAC in girls

   

 Normal pre-pregnancy BMI with normal GWG

75

Ref.

Ref.

 Normal pre-pregnancy BMI with inadequate GWG

45

− 0.19 (− 2.30, 1.92)

− 0.17 (− 2.60, 2.26)

 Normal pre-pregnancy BMI with excessive GWG

46

0.99 (− 1.11, 3.09)

− 0.32 (− 2.71, 2.07)

 Prepregnancy underweight with normal GWG

20

2.79 (− 0.03, 5.61)

3.11 (− 0.29, 6.51)

 Pre-pregnancy overweight or obesity with normal GWG

13

0.86 (− 2.51, 4.23)

0.23 (− 3.64, 4.11)

AGDAF in girls

   

 Normal pre-pregnancy BMI with normal GWG

75

Ref.

Ref.

 Normal pre-pregnancy BMI with inadequate GWG 4

45

0.17 (− 1.25, 1.59)

− 0.85 (− 2.53, 0.83)

 Normal pre-pregnancy BMI with excessive GWG 6

46

− 0.26 (− 1.67, 1.15)

− 1.51 (− 3.16, 0.13)

 Pre− pregnancy underweight with normal GWG 2

20

0.94 (− 0.96, 2.83)

− 1.03 (− 3.38, 1.31)

 Pre-pregnancy overweight or obesity with normal GWG 8

13

− 0.52 (− 2.79, 1.74)

− 1.26 (− 3.94, 1.41)

  1. a68 boys and 44 girls were not included in adjusted analyses due to missing values in covariates
  2. bAdjusted for maternal age at conception, gestational weeks at birth, education, parity, folic acid intake during pregnancy, passive smoking and infant birth weight
  3. *p < 0.05