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Table 1 Oocyte and embryo characteristics of the patient

From: A novel homozygous mutation in the PADI6 gene causes early embryo arrest

Patient

Age (years)

Infertility duration (Years)

Retrieved oocytes

GV oocytes

MI oocytes

MII oocytes

Embryo outcomes on Day 1

Embryo outcomes on Day 2

Embryo outcomes on Day 3

Embryo outcomes on Day 5

Proband

34

15

15

3

0

12

8 × 2PN, 1 × 1PN, 1 × 3PN, 1 × 2-cell

1 × 2-cell, 2 × 3-cell (being implanted), 1 × 4-cell, 3 × fragmentation, 1 × polynucleation

2 × 3-cell (developed from MII oocyte and an embryo with polynuleation, respectively), 1 × 4-cell, 1 × 5-cell

No viable blastocytes

  1. GV, germinal vesicle; MI, metaphase I; MII, metaphase II; PN, pronucleus