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Table 1 Evidence-based preconception care interventions to address health problems contributing to maternal and child mortality

From: Preconception care: advancing from ‘important to do and can be done’ to ‘is being done and is making a difference’

Problems that can be addressed by preconception care interventions

Examples of evidence-based interventions

Nutritional deficiencies and disorders

• Screening for anaemia and diabetes

• Supplementing iron and folic acid

• Information, education and counselling

• Monitoring nutritional status

• Supplementing energy- and nutrient-dense food

• Management of diabetes, including counselling people with diabetes mellitus

• Promoting exercise

• Iodization of salt

Vaccine-preventable infections

• Vaccination against rubella

• Vaccination against tetanus and diphtheria

• Vaccination against Hepatitis B

Tobacco use

• Screening of women and girls for tobacco use (smoking and smokeless tobacco) at all clinical visits using “5 As” (ask, advise, assess, assist, arrange)

• Providing brief tobacco cessation advice, pharmacotherapy (including nicotine replacement therapy, if available) and intensive behavioural counselling services

• Screening of all non-smokers (men and women) and advising about harm of second-hand smoke and harmful effects on pregnant women and unborn children

Environmental risks

• Providing guidance and information on environmental hazards and prevention

• Protecting from unnecessary radiation exposure in occupational, environmental and medical settings

• Avoiding unnecessary pesticide use/providing alternatives to pesticides

• Protecting from lead exposure

• Informing women of childbearing age about levels of methyl mercury in fish

• Promoting use of improved stoves and cleaner liquid/gaseous fuels

Genetic disorders

• Taking a thorough family history to identify risk factors for genetic conditions

• Family planning

• Genetic counselling

• Carrier screening and testing

• Appropriate treatment of genetic conditions

• Community-wide or national screening among populations at high risk

Early pregnancies, unwanted pregnancies, and rapid successive pregnancies

• Keeping girls in school

• Influencing cultural norms that support early marriage and coerced sex

• Providing age-appropriate comprehensive sexuality education

• Providing contraceptives and building community support for preventing early pregnancy and contraceptive provision to adolescents

• Empowering girls to resist coerced sex

• Engaging men and boys to critically assess norms and practices regarding gender-based violence and coerced sex

• Educating women and couples about the dangers to the baby and mother of short birth intervals

Sexually transmitted infections

• Providing age-appropriate comprehensive sexuality education and services

• Promoting safe sex practices through individual, group and community-level behavioural interventions

• Promoting condom use for dual protection against STIs and unwanted pregnancies

• Ensuring increased access to condoms

• Screening for STIs

• Increasing access to treatment and other relevant health services

HIV

• Family planning

• Promoting safe sex practices and dual method for birth control (with condoms) and STI control

• Provider-initiated HIV counselling and testing, including male partner testing

• Providing antiretroviral therapy for prevention and pre-exposure prophylaxis

• Providing male circumcision

• Providing antiretroviral prophylaxis for women not eligible for, or not on, antiretroviral therapy to prevent mother-to-child transmission

• Determining eligibility for lifelong antiretroviral therapy

Infertility and subfertility

• Creating awareness and understanding of fertility and infertility and their preventable and unpreventable causes

• Defusing stigmatization of infertility and assumption of fate

• Screening and diagnosis of couples following 6–12 months of attempting pregnancy, and management of underlying causes of infertility/sub-fertility, including past STIs

• Counselling for individuals/couples diagnosed with unpreventable causes of infertility/sub-fertility

Female genital mutilation

• Discussing and discouraging the practice with the girl and her parents and/or partner

• Screening women and girls for FGM to detect complications

• Informing women and couples about complications of FGM and about access to treatment

• Carrying out defibulation of infibulated or sealed girls and women before or early in pregnancy

• Removing cysts and treating other complications

Mental health disorders

• Providing educational and psychosocial counselling before and during pregnancy

• Counselling and treating depression in women planning pregnancy and other women of childbearing age

• Strengthening community networks and promoting women’s empowerment

• Improving access to education for women of childbearing age

• Reducing economic insecurity of women of childbearing age

Psychoactive substance use

• Screening for substance use

• Providing brief interventions and treatment when needed

• Treating substance use disorders, including pharmacological and psychological interventions

• Providing family planning assistance for families with substance use disorders (including postpartum and between pregnancies)

• Establishing prevention programmes to reduce substance use in adolescents

Interpersonal violence

• Health promotion to prevent dating violence

• Providing age-appropriate comprehensive sexuality education that addresses gender equality, human rights, and sexual relations

• Combining and linking economic empowerment, gender equality and community mobilization activities

• Recognizing signs of violence against women

• Providing health care services (including post-rape care), referral and psychosocial support to victims of violence

• Changing individual and social norms regarding drinking, screening and counselling of people who are problem drinkers, and treating people who have alcohol use disorders