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Table 1 The clinical, hormonal and metabolic parameters in patients with PCOS and control women

From: A case–control observational study of insulin resistance and metabolic syndrome among the four phenotypes of polycystic ovary syndrome based on Rotterdam criteria

Variables PCOS(n = 263) Control(n = 263) P-value
Age (years) 26.78 ± 4.95 29.02 ± 6.04 <0.001
Waist (cm) 99.29 ± 13.30 93.25 ± 12.05 <0.001
Waist-hip ratio (WHR) 0.91 ± 0.75 0.89 ± 0.69 <0.001
BMI (kg/m2) 31.08 ± 5.82 28.66 ± 5.04 <0.001
Systolic blood pressure (mmHg) 125.04 ± 11.94 123.25 ± 11.28 0.078
Diastolic blood pressure (mmHg) 82.21 ± 8.07 81.29 ± 7.43 0.178
AMH (ng/mL) 5.39 ± 2.02 2.49 ± 1.72 <0.001
Total testosterone (ng/mL) 0.44 ± 0.21 0.27 ± 0.13 <0.001
SHBG (nmol/L) 28.01 ± 22.09 41.08 ± 32.39 <0.001
Glucose metabolism profile  
Fasting insulin (FI) (μU/ml) 15.98 ± 10.12 10.75 ± 5.62 <0.001
2-h insulin (2-h I) (μU/ml) 93.79 ± 69.33 59.15 ± 39.24 <0.001
Fasting glucose (FG) (mg/dL) 90.96 ± 16.72 90.01 ± 12.30 0.458
2-h glucose (2-h G)(mg/dL) 126.44 ± 46.75 116.06 ± 28.56 0.002
QUICKI 0.37 ± 0.03 0.34 ± 0.03 0.001
Ratio of 2-h glucose to 2-h insulin 1.96 ± 1.35 2.58 ± 1.40 <0.001
Fasting glucose/fasting insulin 7.74 ± 5.24 10.61 ± 5.88 <0.001
HOMA-IR 3.67 ± 2.683 2.41 ± 1.42 <0.001
HOMA-B 227.99 ± 154.67 161.94 ± 105.27 <0.001
Matusda index 5.21 ± 3.75 7.19 ± 4.13 0.005
Insulin resistance (IR) 112 (42.6) 45 (17.1) <0.001
Normal GTT 176 (66.9) 196 (74.5) 0.105
Prediabetes (IFG and/or IGT) 75 (28.5) 61 (23.2)
Type 2 diabetes mellitus 12 (4.6) 6 (2.3)
Family history of T2DM 131 (49.8) 104 (39.5) 0.022
Lipid profile    
Total cholesterol (TC) (mg/dL) 173.30 ± 34.86 165.29 ± 32.59 0.018
Triglycerides (TG) (mg/dL) 125.73 ± 87.01 96.73 ± 57.15 <0.001
HDL (mg/dL) 43.69 ± 9.68 45.22 ± 8.85 0.059
LDL (mg/dL) 81.55 ± 23.83 77.31 ± 21.87 0.034
Cardiovascular risk (TG/HDL) 3.17 ± 3.03 2.28 ± 1.61 <0.001
Metabolic syndrome (MetS) 141 (53.6) 86 (32.7) <0.001
  1. Values are presented as mean ± standard deviation or number (%). P-values were calculated using Student’s t- test and Chi-square test.