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Table 3 Comparison of seminal analysis parameters between subjects with different genotypes of CYP1A1 gene polymorphisms

From: Effect of CYP1A1 gene polymorphism and psychological distress on seminal analysis parameters

 

For CYP1A1*4 C > A

For CYP1A1*2C A > G

 

Genotype

N

Median (range)

P-value*

Genotype

N

Median (range)

P-value*

Sperm Count (x 106/ml)

CC

24

63 (2.5–125)

0.003

AA

16

70 (2.5–125)

<0.001

 

AC

49

10 (0–140)

 

AG

55

20 (0–105)

 
 

AA

07

45 (1.5–90)

 

GG

09

62 (5–140)

 

Sperm Motility (%)

        

Progressive Motility

CC

24

59 (15–95)

0.003

AA

16

63.5 (10–90)

0.016

 

AC

49

25 (0–95)

 

AG

55

30 (0–95)

 
 

AA

07

40 (10–80)

 

GG

09

60 (5–78)

 

b) Non- progressive

CC

24

20 (5–40)

0.410

AA

16

17.5 (5–70)

0.933

 

AC

49

18 (0–70)

 

AG

55

20 (0–70)

 
 

AA

07

20 (5–70)

 

GG

09

20 (0–40)

 

c) Immotile

CC

24

20 (0–70)

0.305

AA

16

20 (5–30)

0.290

 

AC

49

20 (0–95)

 

AG

55

25 (0–95)

 
 

AA

07

25 (5–60)

 

GG

09

16 (0–70)

 

Sperm Morphology

        

Normal

CC

24

59 (5–92)

0.074

AA

16

61.5 (5–98)

0.056

 

AC

49

32 (0–95)

 

AG

55

40 (0–90)

 
 

AA

07

58 (0–98)

 

GG

09

66 (25–95)

 

b) Abnormal

CC

24

49 (8–95)

0.108

AA

16

38.5 (2–95)

0.196

 

AC

49

60 (0–98)

 

AG

55

55 (0–98)

 
 

AA

07

42 (2–92)

 

GG

09

34 (5–75)

 
  1. *P value calculated by Kruskal wallis test