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Table 1 Summary of approaches to measuring adherence to different contraceptive methods

From: Assessing the validity and reliability of self-report data on contraception use in the MObile Technology for Improved Family Planning (MOTIF) randomised controlled trial

Contraceptive method

Measurement approach

Advantages

Disadvantages

Oral Contraceptive

Direct observation (clinician observes ingestion of pill)

Accurate and equates to ingestion

Impractical

Self-reports (self-completed or interview administered questionnaire)

Simple, inexpensive and easy to administer.

Requires training for administrators. Subject to recall and social desirability bias.

Clinic / pharmacy records

Can help to correct poor recall. Simple, inexpensive and objective. Usually easy to obtain data. Can measure at more than one point in time.

Does not equate to ingestion and requires a closed pharmacy system

Pill counts (individual pill or pill pack counts)

Objective; quantifiable and easy to perform.

However, easily altered by participant (e.g. pill dumping), cannot assess timing of use

Electronic Monitoring Devices

Objective, precise, tracks patterns of use over time.

Potentially expensive and may require return visits to download data. Participants may not adhere to using device, intervention might improve use of device rather than pill-taking behaviour.

Blood hepatic binding globulin levels (Corticosteroid Binding Globulin, Thyroxine Binding Globulin, Lutenizing Hormone and Sex Hormone Binding Globulin)

Objective. Can distinguish between consistent use and non-use (Corticosteroid Binding Globulin and Thyroxine Binding Globulin more discriminating). Inexpensive compared to measuring contraceptive steroid level

Requires specialist laboratory. Can’t distinguish between consistent and inconsistent users

Blood contraceptive steroid level (e.g. Levonorgestrel or Ethinylestradiol)

Objective, indicates indigestion.

Difficult test, expensive therefore limited potential for replication in other studies, requires a blood test, will not distinguish consistent from inconsistent users

IUD / implant

Self-report

Simple, inexpensive and easy to administer.

Subject to recall bias and social desirability bias

Clinical examination or ultrasound

Simple, inexpensive and easy to administer.

Intrusive, has to be performed in clinic setting, requires skilled personnel/ equipment

Clinic or client record

Objective

Requires a closed pharmacy system. Self-held record can get lost

Injection

Self-report

Simple, inexpensive and easy to administer.

Subject to recall bias and social desirability bias.

Clinic or clinic record

Objective and indicates current use

Requires a closed pharmacy system. Self-held record can get lost