Table 3 Site-specific methods, the Pregnancy and Influenza Multinational Epidemiologic Study
| Â | Bangkok, Thailand | Lima, Peru | Nagpur, India |
|---|---|---|---|
Recruitment and enrollment | |||
 Enrollment period, year 1 (epidemiologic weeks) | 20–32 | 11–22 | 19–30 |
 Additional eligibility requirements | Ability to speak and understand Thai | None | Resident of urban Nagpur, Access to mobile phone |
 Recruitment setting | Antenatal care clinic | Antenatal care clinc, Preventive care medicine clinic | Antenatal care clinic |
 Method of identifying potentially eligible women | Review of medical record and antenatal clinic cards | Staff maintain list of all women seen in the clinics each day | Staff maintain list of all women seen in the clinics each day |
 Method of sampling women for recruitment | None, attempt to approach all women | Sample every 3rd woman during high patient volume periods, otherwise, attempt to approach all women | None, attempt to approach all women |
Gestational age dating by ultrasound | |||
 Personnel primarily responsible for performing ultrasound | Hospital ultrasonographers trained on gestational age dating SOP | Hospital ultrasonographers trained on gestational age dating SOP | Private ultrasonographers hired for study and trained on gestational age dating SOP |
Surveillance for ILS | |||
 Primary method of contact with participants | Telephone calls | Telephone calls | Telephone calls, Home visits |
 Additional methods used by participants to report illness | Telephone calls to study nurses | Telephone calls or text messaging application to study staff | Telephone hotline to study staff Customized electronic application |
 Method of nasal swab collection | Participant self-collection | Study staff collection | Study staff collection |
End of pregnancy or delivery | |||
 Methods of identifying end of pregnancy or delivery | Surveillance contacts, Medical records flagged so hospital staff recognize study participants at delivery and can communicate with study team | Surveillance contacts, Review of labor room records | Surveillance contacts, Telephone hotline for participants and family to call Medical records flagged so hospital staff recognize study participants at delivery and can communicate with study team Review of labor room records |
 Primary location of deliveries | Hospital | Hospital | Hospital |
 Birthweights, personnel primarily responsible for collection | Delivery nurses trained on birthweight collection SOP | Delivery nurses trained on birthweight collection SOP | Delivery nurse midwives and study staff trained on birthweight collection SOP |
Chart abstraction data sources | Delivery hospitalization records Antenatal clinic records | Delivery hospitalization records Antenatal clinic records National prenatal care card | Delivery hospitalization records Antenatal clinic records |
Influenza vaccine verification sources | Hospital records | National prenatal care card Hospital records | Hospital records Antenatal clinic records Immunization cards |
Additional substudy activities | |||
 Serology specimen collection for serology substudy | Yes | Yes | No |
 Testing nasal swabs for other respiratory viruses | Yes (hMPV, RSV) | No | No |