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Table 2 Risk of bias in randomized and non-randomized trials

From: A systematic review on clinical effectiveness, side-effect profile and meta-analysis on continuation rate of etonogestrel contraceptive implant

Criteria for Randomized control trials Dan Apter 2016 David Hubacher 2017
Random sequence generation (selection bias) Low risk Low risk
Allocation concealment (selection bias) Low risk Low risk
Blinding of participants and personnel (performance bias) High risk High risk
Blinding of outcome assessment (detection bias) High risk Low risk
Incomplete outcome data (attrition bias) High risk High risk
Selective reporting (reporting bias) Low risk Low risk
Other bias NA NA
Over all High risk High risk
Criteria for Non-Randomized control trials Bahamondes 2015 Flores 2005 Oderich 2012
 Bias due to confounding Moderate risk NI (No info) NI (No info)
 Bias in selection of participants into the study Moderate risk NI (No info) NI (No info)
 Bias in classification of interventions Low risk Low risk Low risk
 Bias due to deviations from intended interventions Low risk Low risk Low risk
 Bias due to missing data Moderate risk NI (No info) Low risk
 Bias in selection of the reported result Low risk Low risk Low risk
 Overall Moderate risk Serious risk Serious risk