Fertility treatments and the risk of preterm birth among women with subfertility: a linked-data retrospective cohort study

Table 3 Birth outcomes by infertility diagnosis (N = 490)

	Term		Preterm		Total		P value*
	N	Row%	N	Row%	N	Col%	P value*
Tubal factor
No	341	82.8%	71	17.2%	412	84.1%	0.044
Yes	57	73.1%	21	26.9%	78	15.9%
Endometriosis
No	299	83.3%	60	16.7%	359	73.3%	0.053
Yes	99	75.6%	32	24.4%	131	26.7%
Ovulation dysfunction
No	190	84.1%	36	15.9%	226	46.1%	0.135
Yes	208	78.8%	56	21.2%	264	53.9%
Uterine factor
No	347	81.6%	78	18.4%	425	86.7%	0.540
Yes	51	78.5%	14	21.5%	65	13.3%
Male factor
No	243	82.4%	52	17.6%	295	60.2%	0.423
Yes	155	79.5%	40	20.5%	195	39.8%
Unexplained infertility
No	235	81.9%	52	18.1%	287	59.5%	0.604
Yes	156	80.0%	39	20.0%	195	40.5%
Multiple female factors
No	294	83.5%	58	16.5%	352	71.8%	0.037
Yes	104	75.4%	34	24.6%	138	28.2%
Multiple female and male factors
No	299	83.1%	61	16.9%	360	73.5%	0.084
Yes	99	76.2%	31	23.8%	130	26.5%
Total	398	81.2%	92	18.8%	490	100.0%

*χ² comparing to women who were not told or suspect diagnosis
∙ Diagnostic categories—SART CORS classification
– Tubal factor—pelvic adhesion or scarring, blocked or damaged fallopian tubes
– Endometriosis
– Ovulation dysfunction—low progesterone, low estrogen, not ovulating, abnormal ovulation, lutenized unruptured follicule (LUF), Luteal Phase Defect (LUD), PCOS
– Uterine factor—hostile or limited cervical mucus, fibroids in the uterus, polyps in the uterus,
– Male factor
– Unknown infertility—unexplained subfertility
– Multiple female factors—more than one of the following diagnosis Tubal, Endometriosis, Ovulation dysfunction, or Uterine
– Female and male factor—male factor plus at least one female factor

ISSN: 1742-4755