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Table 2 Menstrual and medical history of women

From: Incidence and risk factors of infertility among couples who desire a first and second child in Shanghai, China: a facility-based prospective cohort study

 

All couples

P valuec

First child intention

P valuec

Second child intention

P valuec

Infertilitya (N = 369)

Fertility (N = 1808)

Infertilitya (N = 355)

Fertility (N = 1484)

Infertilitya (N = 14)

Fertility (N = 324)

nb (%)

nb (%)

nb (%)

nb (%)

nb (%)

nb (%)

Menstrual history

 Menarche (year)

  < 13

49 (14.63)

225 (13.71)

0.101

46 (14.56)

171 (12.85)

0.319

2 (14.29)

53 (17.32)

< 0.001

  13–14

245 (73.13)

1273 (77.57)

234 (74.05)

1037 (12.85)

7 (50.00)

234 (76.47)

  > 14

41 (12.23)

143 (8.71)

36 (11.39)

123 (9.24)

5 (35.71)

19 (6.21)

 Menstrual cycle (days)

  21–35

278 (81.52)

1556 (93.29)

< 0.001

259 (80.43)

289 (92.99)

< 0.001

14 (100.00)

289 (94.44)

1.000

  > 35

63 (18.48)

112 (6.72)

63 (19.57)

95 (7.01)

0 (0)

17 (5.56)

 Menstrual duration (days)

  2–7

317 (92.69)

1629 (97.60)

< 0.001

299 (92.57)

1328 (98.23)

< 0.001

13 (92.86)

294 (95.77)

0.471

  > 7

25 (7.31)

40 (2.40)

24 (7.43)

24 (1.77)

1 (7.14)

13 (4.23)

 Dysmenorrhea

  None

148 (43.529)

728 (43.776)

0.936

139 (43.30)

568 (42.14)

0.894

8 (57.14)

157 (50.97)

0.903

  Occasional

107 (31.471)

508 (30.547)

102 (31.78)

428 (31.75)

3 (21.43)

76 (24.68)

  Regular

85 (25.000)

427 (25.676)

80 (24.92)

352 (26.11)

3 (21.43)

75 (24.35)

Gynecological history

 Pelvic inflammationd

  No

320 (93.84)

1590 (95.21)

0.292

303 (93.81)

1292 (95.56)

0.191

12 (92.31)

293 (94.21)

0.551

  Yes

21 (6.16)

80 (4.79)

20 (6.19)

60 (4.44)

1 (7.69)

18 (5.79)

 Adenomyosisd

  No

340 (97.98)

1671 (99.10)

0.047

335 (97.95)

1426 (99.03)

0.157

14 (100)

318 (100)

NA

  Yes

7 (2.02)

14 (0.83)

7 (2.05)

14 (0.97)

0 (0)

0 (0)

 Leiomyomad

  No

301 (83.15)

1607 (90.84)

< 0.001

287 (83.67)

1301 (90.16)

0.001

10 (71.43)

299 (93.73)

0.013

  Yes

61 (16.85)

162 (9.16)

56 (16.33)

142 (9.84)

4 (28.57)

20 (6.27)

 Ovarian cystd

  No

308 (85.32)

1624 (91.96)

< 0.001

293 (85.67)

1328 (92.16)

< 0.001

13 (92.86)

291 (91.51)

1.000

  Yes

53 (14.68)

142 (8.04)

49 (14.33)

113 (7.84)

1 (7.14)

27 (8.49)

 Endometrial polypd

  No

309 (90.62)

1616 (97.12)

< 0.001

291 (90.37)

1307 (97.10)

< 0.001

13 (92.86)

304 (97.75)

0.3

  Yes

32 (9.38)

48 (2.89)

31 (9.63)

39 (2.90)

1 (7.14)

7 (2.25)

 Endometriosisd

  No

320 (93.57)

1637 (98.08)

< 0.001

304 (94.12)

1320 (97.71)

0.002

13 (92.86)

310 (99.68)

0.084

  Yes

22 (6.43)

32 (1.92)

19 (5.88)

31 (2.29)

1 (7.14)

1 (0.32)

 PCOSd

  No

311 (86.15)

1721 (97.51)

< 0.001

292 (85.38)

1407 (97.71)

< 0.001

14 (100)

307 (96.54)

1.000

  Yes

50 (13.85)

44 (2.49)

50 (14.62)

33 (2.29)

0 (0)

11 (3.46)

Surgical history

 Uterine myomectomye

  No

335 (96.54)

1670 (99.05)

0.001

317 (96.65)

1352 (98.98)

0.004

14 (100)

311 (99.36)

1.000

  Yes

12 (3.46)

16 (0.95)

11 (3.35)

14 (1.02)

0 (0)

2 (0.64)

 Salpingostomye

  No

323 (93.08)

1663 (98.64)

< 0.001

13 (92.86)

1347 (98.61)

< 0.001

13 (92.86)

309(98.72)

0.198

  Yes

24 (6.92)

23 (1.36)

22 (6.71)

19 (1.39)

1 (7.14)

4(1.28)

 Endometrial polypectomye

  No

333 (95.97)

1666 (98.81)

< 0.001

315 (96.04)

1349 (98.76)

0.004

14 (100)

309 (98.72)

1.000

  Yes

14 (4.04)

20 (1.19)

13 (3.96)

17 (1.24)

0 (0)

4 (1.28)

 Hysteroscopic adhesiolysise

  No

339 (97.70)

1673 (99.23)

0.037

320 (97.56)

1354 (99.12)

0.039

14 (100)

312 (99.68)

NA

  Yes

8 (2.31)

13 (0.77)

8 (2.44)

12 (0.88)

0 (0)

1 (0.32)

Genital tract infection history

 TPe

  No

345 (99.424)

1682 (99.763)

0.605

341 (99.42)

1446 (99.72)

0.323

14 (100)

320 (100)

NA

  Yes

2 (0.576)

4 (0.237)

2 (0.58)

4 (0.28)

0 (0)

0 (0)

 Herpes viruse

  No

345 (99.424)

1685 (99.941)

0.077

341 (99.42)

1449 (99.93)

0.096

14 (100)

320 (100)

NA

  Yes

2 (0.576)

1 (0.059)

2 (0.58)

1 (0.07)

0 (0)

0 (0)

 Mycoplasma genitaliume

  No

291 (80.387)

1504 (84.637)

0.045

274 (79.88)

1220 (84.14)

0.064

13 (92.86)

278 (86.88)

1.000

  Yes

71 (19.613)

273 (15.363)

69 (20.12)

230 (15.86)

1 (7.14)

42 (13.13)

 Chlamydia genitaliume

  No

340 (93.923)

1716 (96.894)

0.006

321 (93.59)

1396 (96.61)

0.010

14 (100)

313 (98.12)

1.000

  Yes

22 (6.077)

55 (3.106)

22 (6.41)

49 (3.39)

0 (0)

6 (1.88)

 Condyloma acuminatae

  No

343 (98.847)

1681 (99.703)

0.081

339 (98.83)

1446 (99.72)

0.048

14 (100)

319 (99.69)

NA

  Yes

4 (1.153)

5 (0.297)

4 (1.17)

4 (0.28)

0 (0)

1 (0.31)

 HPVe

  No

341 (98.271)

1663 (98.636)

0.784

338 (98.54)

1433 (98.83)

0.593

14 (100)

314 (98.13)

1.000

  Yes

6 (1.729)

23 (1.364)

5 (1.46)

17 (1.17)

0 (0)

6 (1.88)

  1. PCOS polycystic ovarian syndrome, TP treponema pallidum antibody, HPV high-risk human papillomavirus
  2. aFaliure to conceive after regular unprotected sexual intercourse for 1 year
  3. bThe sum does not necessarily equal the sample size for all variables because of missing data
  4. cPearson’s χ2 test
  5. dThe diagnosis standard referred to the Dutch Rotterdam diagnostic criteria
  6. eMake negative results as reference groups