Fig. 3
From: A novel homozygous mutation in the PADI6 gene causes early embryo arrest
The locations and conservation of mutated residues position in PADI6. a The localization of the mutations is indicated in the genomic and protein structure of PADI6. b Conservation of amino acids in PADI6 among different 8 mammalian orthologs. c Protein conformation prediction of the effect of mutation in PADI6. The view shows the structure comparison of structure of the frameshift insertion mutation in PADI6 protein with wild-type PADI6 protein