Open Access
Open Peer Review

This article has Open Peer Review reports available.

How does Open Peer Review work?

Adverse obstetric symptoms and rural–urban difference in cesarean delivery in Rupandehi district, Western Nepal: a cohort study

  • Vishnu Khanal1Email author,
  • Rajendra Karkee2,
  • Andy H. Lee3 and
  • Colin W Binns3
Reproductive Health201613:17

https://doi.org/10.1186/s12978-016-0128-x

Received: 7 August 2015

Accepted: 11 February 2016

Published: 1 March 2016

Abstract

Background

The burden of maternal morbidity is high in developing countries including Nepal. This study investigated obstetric complications and rural–urban difference in cesarean delivery rate in Western Nepal.

Methods

A community-based cohort study was conducted in the Rupandehi district of Western Nepal during January-October, 2014, by interviewing 735 mothers within one month postpartum. The prevalence of obstetric complications was reported via frequency distribution, while factors associated with cesarean delivery were assessed using logistic regression analysis.

Results

The prevalence of adverse obstetric symptoms during antenatal, intranatal and postnatal periods were 19.7 %, 27.8 % and 21.6 %, respectively. In total, 81 (11.0 %) mothers reported having stillbirths. The cesarean delivery rate was 14.1 % overall but was four times higher in the urban (23.0 %) than in the rural areas (5.8 %). Prolonged labor (19.0 %) and heavy bleeding (16.7 %) were common among rural women. Logistic regression analysis confirmed that cesarean section was more likely for mothers residing in urban areas than in rural areas (adjusted odds ratio 3.41; 95 % confidence interval 2.01 to 5.78).

Conclusions

About one in five mothers reported some adverse obstetric symptoms. Obstetric problems were more common in the rural areas, whereas cesarean delivery rate was much higher in the urban areas. Further investigations are required to determine whether these cesarean sections are medically warranted or provider induced.

Keywords

Cesarean section Maternal health Nepal Obstetric complications Stillbirth

Background

Worldwide, maternal mortality has fallen substantially at an annual rate of 1.3 % since 1990 [1]. In developing countries, the maternal mortality ratio was 283.2 per 100,000 live births in 1990 and decreased to 209.1 in 2013 [1]. Despite such progress, about 15 % of women suffer obstetric complications every year [2], while the burden of maternal morbidity remains high in developing countries, the consequences of which include infertility, psychological effects, disability, and loss of quality of life [3].

Nepal has achieved great success in reducing maternal mortality since 1990, notwithstanding severe political unrest, unstable economy and poor health infrastructure [4]. The maternal mortality ratio was 850 per 100,000 live births in 1990, reduced to 281 in 2005, and 170 by 2013 [5]. However, a recent survey in 2009 reported that 41 % of maternal deaths occurred in health facilities and 40 % at the home, suggesting that early notification and response to danger signs in these settings are essential to save the lives of Nepalese mothers [6].

With increasing health facility deliveries, the cesarean section rates in Nepal are also rising. There is some concern that the increase could be due to more planned or provider initiated operations rather than medically indicated [7]. In resource poor settings such as Nepal, provider-induced cesarean sections are likely to exert additional pressure on the already stretched health system. Therefore, monitoring of the cesarean delivery rate is important to ensure health equity particularly for disadvantaged populations and vulnerable groups, and that maternity services are being provided thoughtfully. It has been reported that 40 % of women experienced a serious illness during pregnancy and childbirth [8], while 21.1 %, 24.4 %, and 10.2 % of mothers had suffered from obstetric problems related to childbirth during the antenatal, intranatal and postnatal periods, respectively [7]. The present study aimed to determine the prevalence of obstetric complications and to investigate the rural–urban difference in cesarean delivery in Western Nepal. In view of the recent major earthquake which has destroyed infrastructure and many health facilities across the country [9, 10], our results are particularly timely and important to arouse worldwide attention to the problem.

Methods

Study setting

The Rupandehi district lies in south-western Nepal, with relatively good access to hospitals and other health facilities in the region. The district has three referral hospitals and one district hospital in urban areas, and five primary health care centers, six health posts and 58 sub-health posts in rural areas, providing services to its population of 880,196 (432,193 males, 448,003 females) [11, 12]. According to the 2009 Maternal Mortality and Morbidity Survey, the Rupandehi district has a higher maternal mortality (274 per 100,000 live births) than the national average (229 per 100,000 live births) [6]. The district is predominantly ‘rural’ consisting of village development committees, whereas ‘urban’ is defined as municipalities. While each village development committee has at least one government facility, health posts and sub-health posts do not have doctors and nurses stationed to provide full maternity services. Similarly, primary health care centers are not equipped to perform cesarean sections, unlike urban hospitals. Most rural areas are linked to the cities by gravel roads. Public transport is often irregular and non-functional during the rainy season due to road blockades, and therefore cannot be relied upon for medical emergencies. When public transport runs smoothly, it takes one-day travel to reach the nearby city from some of the rural areas for referral services.

Participants and procedure

A cohort study was conducted in the Rupandehi district during January-October, 2014. Fig. 1 explains the process of recruitment of participants [13]. Briefly, the total population of expected infants (<1 year) was 20,061 in 2014 [Source: District Public Health Office, Rupandehi, Annual Target 2013/2014]. A total of 735 mother-infant pairs (rural 378, urban 357) were recruited from 15 randomly selected village development committees and 12 communities of two municipalities. A few urban women (n = 18) declined to be interviewed whereas all women participated in the rural areas [14]. Lists of eligible mothers were compiled in the selected areas with the help of local female community volunteers. Recruitment from each community was proportionate to its number of expected infants per month. The inclusion criteria were: singleton birth; age of infant <30 days; resident of the community; and the child was alive at the time of recruitment.
Fig. 1

Study flow chart

Face-to-face interviews were conducted by trained female enumerators using questions adapted from the Nepal Demographic and Health Survey [15] and a previous questionnaire validated in central Nepal [7]. To obtain information on obstetric complications, common symptoms were read to mothers so that they could respond ‘yes’ or ‘no’ [16]. The list included: (1) antenatal: heavy bleeding (soaked clothes/bed/floor), swollen hands, fits or loss of consciousness, blurred vision, severe headache, severe fever, severe abdominal pain, and severe vomiting; (2) intranatal: heavy bleeding(soaked clothes/bed/floor), prolonged labor (12 hours or more), retained placenta (placenta not delivered within 30 minutes), swollen hands, and fits or loss of consciousness; (3) postnatal: heavy bleeding (soaked clothes/bed/floor), severe fever, foul smelling watery discharge, swollen hands, and fits or loss of consciousness. The choice was spontaneous and also kept as open ended to allow the recording of signs and symptoms not captured by our questionnaire. However, confirmation of obstetric morbidities through clinical audit was not feasible. Ethics approval of the study protocol was obtained from the Nepal Health Research Council (773/2014) and the Human Research Ethics Committee of Curtin University (approval number HR184/2013). Mothers provided consent for themselves. Personal identifiers were removed from the dataset before statistical analyses and only aggregated data were reported.

Definitions and variables

The outcome variables were complications during pregnancy and childbirth. The method of delivery was either cesarean or vaginal. Stillbirth was specified as death of a fetus after 28 weeks of gestation [17] and recorded for the previous birth only. Prolonged labor was defined as lasting12 hours or more. Heavy bleeding was defined as bleeding that soaked clothes, bed or floor of the room [7].

Independent variables were identified based on literature review. We recoded maternal age (years) as: 15–19, 20–29, and 30–45; maternal education as: ‘no education’ , ‘primary/lower secondary’ (up to grade 8), ‘secondary’ (grade 9–10) and ‘higher’ (grade 11–12 and university degree). Paternal occupation was classified as: ‘employed’ (salaried job), ‘semi-employed’ (labor, business and foreign labor), and ‘unemployed’ (no paid job, and unpaid subsistent agriculture). Household assets (water source, toilet facility, types of cooking fuel, separate kitchen, floor material, electricity, radio, television, mobile phones and cupboard) were assigned scores using principal component analysis to generate a wealth index, which was then categorized into the lowest (poorest) to the highest (richest) quintile [16] and further re-grouped into three levels to facilitate analysis: ‘poor’ (lowest 40 %), ‘middle’ (middle 40 %) and ‘rich’ (upper 20 %) [18].

Statistical analysis

The prevalence of obstetric complications, stillbirth and cesarean delivery were reported as the proportion of participants in this study. The rural–urban difference in cesarean section rate was confirmed by a multivariable logistic regression model with the backward stepwise method to control for confounding variables. All data analyses were performed using the Statistical Package for Social Sciences (IBM, SPSS version 20).

Results

A total of 735 participants were enrolled in the study, whose characteristics are presented in Table 1. The average age was 24.6 (SD 4.6) years, with the majority (74.8 %) within the 20–25 years age group. About a quarter (26.0 %) of the women had no formal education. Most of their partners (70.0 %) were semi-employed, and one-fifth of participants (19.8 %) came from rich families. In terms of antenatal care, the great majority (76.2 %) of mothers paid four or more visits. In total, 314 (42.8 %) of them were primiparous and 88.2 % delivered in a health facility.
Table 1

Characteristics of participants, Nepal (n = 735)

Characteristics

Frequency

Percentage

Maternal agea

  

 15–19 years

99

9.0

 20–29 years

549

74.8

 30–45 years

119

16.2

Maternal education

  

 No education

192

26.0

 Primary to lower secondary

243

33.1

 Secondary and above

300

40.8

Paternal occupation

  

 Employed

102

13.9

 Semi-employed

516

70.2

 Unemployed

117

15.9

Place of residence

  

 Rural

378

51.4

 Urban

357

48.6

Wealth status

  

 Poor

295

40.1

 Middle

295

40.1

 Rich

145

19.8

Maternal heighta

  

 <150 cm

254

34.9

 ≥150 cm

474

65.1

Frequency of antenatal care

  

 No visit

17

2.3

 1 to 3 visits

157

21.4

 4 or more visits

558

76.2

Paritya

  

 Primiparous

314

42.8

 Multiparous

420

57.2

aMissing data present

Table 2 lists the adverse obstetric symptoms as reported by our participants. In the antenatal period, 145 mothers (19.7 %) reported complications, compared to 204 (27.8 %) in the intranatal and 159 (21.6 %) in the postnatal period. During the antenatal period, foul smelling vaginal discharge (6.5 %), and swelling of hands (6.1 %) were the most common symptoms. During the intranatal period, prolonged labor (11.3 %), heavy bleeding (10.1 %) and swelling of hands (7.5 %) were commonly reported. During the postnatal period, swelling of hands (7.8 %) and high fever (4.2 %) were the main problems experienced by the mothers. No significant difference in the reported morbidities was found between primi-parous and multiparous woman.
Table 2

Adverse obstetric symptoms during antenatal, intranatal and postnatal periods

Problems

Frequency

Percentage

Antenatal

145

19.7

 Some bleeding

63

8.5

 Heavy bleeding

10

1.3

 High fever

30

4.0

 Foul smelling vaginal discharge

48

6.5

 Swelling of hands

45

6.1

 Fits or loss of consciousness

12

1.6

Intranatal

204

27.8

 Heavy bleeding

74

10.1

 Prolonged labor:12 to 23 hours

83

11.3

 Prolonged labor: 24 to 47 hours

20

2.7

 Prolonged labor: 48 hours or more

13

1.8

 Retained placenta: 30 min to <1 hour

24

3.3

 Retained placenta:1 hour or more

1

0.1

 Swelling of hands

55

7.5

 Fits or loss of consciousness

14

1.9

Postnatal

159

21.6

 Heavy bleeding

12

1.6

 High fever

31

4.2

 Foul smelling discharge

26

3.5

 Swelling of hands

57

7.8

 Fits or loss of consciousness

12

1.6

A total of 81 (11.0 %) mothers reported a stillbirth previously, and 104 (14.1 %) mothers had cesarean section. There was a significant difference in cesarean delivery prevalence by location (p <0.001), with only 22 (5.8 %) of the 378 rural women had cesarean section compared to 82 (23.0 %) of the 357 urban women. On the other hand, prolonged labor (>12 hours) and heavy bleeding appeared to be more common in rural areas, where 72 (19.0 %) rural mothers reported having a prolonged labor as compared to 40 (11.2 %) urban mothers (p = 0.03). Similarly, 63 (16.7 %) rural mothers mentioned the signs of heavy bleeding during the intranatal period, as contrasted to only 11 (3.1 %) mothers residing in urban areas (p < 0.001). As shown in Table 3, logistic regression analysis confirmed the higher risk of incurring a cesarean delivery for these urban women relative to their rural counterparts (adjusted odds ratio 3.41, 95 % confidence interval 2.01 to 5.78).
Table 3

Factors associated with cesarean delivery in Western Nepal

Factors

Adjusted odds ratioa

P

Place of residence

 

<0.001

 Rural

1.00

 

 Urban

3.41 (2.01, 5.78)

 

Maternal education

 

<0.001

 No education

1.00

 

 Primary to lower secondary

0.83 (0.38, 1.83)

 

 Secondary and above

2.56 (1.28, 5.14)

 

Parity

 

0.010

 Multiparous

1.00

 

 Primiparous

1.85 (1.16, 2.95)

 

aIndependent variables excluded from the stepwise logistic regression model were paternal occupation, wealth status, maternal age, frequency of antenatal care, and maternal height

Discussion

An important finding is the unequal distribution of cesarean delivery across rural and urban areas. Rural mothers suffered more from adverse obstetric symptoms during the intranatal period. While the overall cesarean section rate of 14.1 % was within the World Health Organization’s recommended rate of 5 % to 15 % [19], a significantly higher rate of 23 % was evident in urban areas. Our result was consistent with previous studies conducted in South Asia [7, 20].

After a major reform in 2005, the Nepal health care system provides maternity services including cesarean delivery to its citizens free of charge at public facilities [21], and pays an allowance to cover travel expenses of the mother. With such initiatives, facility delivery rate has been successfully increased from 9 % in 2001 [22] to 35.3 % in 2011 [15], and especially high (73.1 %) in some accessible areas of Nepal [23]. Moreover, many public and private hospitals can now perform cesarean sections. Under these circumstances, the higher cesarean delivery rate in urban areas might merely reflect ‘on-demand’ or ‘provider initiated’ without a medical indication. Similar trends have been witnessed in South Asia and elsewhere [20]. Our findings on the rural–urban differentials in cesarean delivery rate and obstetric complications also reflect an uneven distribution of health services in Nepal. Provider-induced cesarean sections have potential adverse consequences, in terms of increasing the health care costs, and unnecessary occupation of hospital beds leading to overcrowding in tertiary hospitals. Further investigations would confirm whether those cesarean sections performed were indeed medically warranted.

Stillbirth is another problem for intervention that has received relatively little attention so far. Our observed prevalence of 11 % in Western Nepal was higher than the previous reported rate of 3.13 % in the Dhanusha district [24] but comparable with another hospital-based estimate of 13.3 % [25]. Recently, a verbal autopsy study to ascertain the causes of neonatal death in 2013 revealed that 37.9 % of the 551 deceased newborns were stillbirths, and fresh stillbirths accounted for 72.7 % of these cases [26]. Such in-depth assessment suggested the necessity to improve quality of care during childbirth, since 45 % of stillbirths could be averted by existing interventions [27]. This has important implications for Nepal because fresh stillbirths remain a major problem yet the quality of care is low during the intranatal period [28].

About one in five mothers reported adverse obstetric symptoms during the antenatal, intranatal and postnatal periods. Our result was similar to that of a previous study conducted in the Kaski district of central Nepal [7], but substantially lower than the 42.9 % postnatal morbidity incidence reported in Gadchiroli, India [29]. It should be remarked that the underlying settings were quite different, especially in terms of place of delivery. While the home delivery rate was only 11.8 % in the present study, it was 94.9 % in Gadchiroli, India. In light of the recent earthquakes, where more than 126,000 pregnant women were adversely affected or displaced, cesarean delivery services have not been restored in most of the earthquake affected districts, while two-third of birth centers were either destroyed or non-functional [30, 31], the progress made in maternal health since the 1990’s may be reversed so that urgent attention is required.

Heavy bleeding and prolonged labor are found to be common obstetric problems, both of which signal an immediate need for emergency obstetric care from skilled birth attendant and possible cesarean section. Although urban hospitals are capable to provide cesarean section and manage obstetric complications, such facilities and services are still lacking in the rural and remote mountainous areas of Nepal. Antenatal screening and early referral of rural mothers at risk would prevent maternal mortality and minimize the severe consequences of maternal morbidity. However, since some of the adverse maternal outcomes such as postpartum hemorrhage and sepsis cannot be predicted by screening alone, provision of emergency obstetric care within reach of the local community is important to save the lives of mothers. Since 2008/2009, the Ministry of Health and Population of Nepal has started allocating special funds for comprehensive emergency obstetric and neonatal care to cover the cost of equipment and health workforce for cesarean delivery [32]. It is still unknown whether this government initiative can reduce the burden of severe intranatal obstetric morbidity.

A major strength of the current study was the short recall time for the obstetric events since all interviews were conducted within 30 days postpartum. It also highlights the rural–urban difference in cesarean delivery rate and the prevalent obstetric complications in the Rupandehi district of Western Nepal, where maternal mortality was significantly higher than the national average [6]. Nevertheless, the self-reporting of signs and symptoms posed as the main limitation. In Nepal where the health information system is poorly maintained, information retrieved from hospital and government databases is unlikely to be accurate and reliable, even though record reviews have been cited as an important data source [33]. Therefore, self-reporting has been commonly relied upon in poor resource settings [7, 29, 34], despite the difficulty to obtain obstetric details from the mothers due to stigma, social and cultural reasons. In this study, the mothers were prompted with a comprehensive list of signs and symptoms that could occur during the antenatal, intranatal and postnatal periods, so that the reported prevalence of such events would reflect the true community situation. Another limitation concerns the lack of data on obstetric and neonatal outcomes such as stillbirth, pre-term birth and early neonatal deaths, without verbal autopsy, clinical audit and access to hospital records. Similarly, detailed investigation of the birth process, including treatment and medication used to augment labor, was not feasible given our budget constraint and available resources. Further studies are recommended to examine these issues especially stillbirths [35] and to confirm the impact of government incentives on cesarean rates.

Conclusion

This study found that about one in five mothers had obstetric complications in Western Nepal. Furthermore, 11 % of mothers reported having a stillbirth, and 14 % of them underwent cesarean section. While prolonged labor and heavy bleeding were more common among rural mothers, the rate of cesarean section was more than four times higher in urban areas than in rural areas. Future public health interventions should focus on increasing access to obstetric services in rural areas, and the prevention of stillbirths through the provision of quality maternity care. Further investigations are also required to determine whether the cesarean sections conducted in urban areas are medically warranted or provider induced.

Details of ethics approval

Nepal Health Research Council (773/2014) and the Human Research Ethics Committee of Curtin University (approval number HR184/2013).

Declarations

Acknowledgements

The authors are grateful to the mothers and their families for participation in the study. Thanks are also due to the District Public Health Office of Rupandehi, and local social activists for their support and assistance with recruitment and data collection.

Funding

None

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Authors’ Affiliations

(1)
Nepal Development Society
(2)
School of Public Health and Community Medicine, BP Koirala Institute of Health Sciences
(3)
School of Public Health, Curtin University

References

  1. Kassebaum NJ, Bertozzi-Villa A, Coggeshall MS, Shackelford KA, Steiner C, Heuton KR, Gonzalez-Medina D, et al. Global, regional, and national levels and causes of maternal mortality during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014;384:980–1004.View ArticlePubMedPubMed CentralGoogle Scholar
  2. Koblinsky M, Chowdhury ME, Moran A, Ronsmans C. Maternal morbidity and disability and their consequences: neglected agenda in maternal health. J Health Popul Nutr. 2012;30:124.View ArticlePubMedPubMed CentralGoogle Scholar
  3. Cham M, Sundby J, Vangen S. Fetal outcome in severe maternal morbidity: too many stillbirths. Acta Obstet Gynecol Scand. 2009;88:343–9.View ArticlePubMedGoogle Scholar
  4. Karkee R, Lee AH, Binns CW. Birth preparedness and skilled attendance at birth in Nepal: Implications for achieving millennium development goal 5. Midwifery. 2013;29:1206–10.View ArticlePubMedGoogle Scholar
  5. Government of Nepal, National Planning Commission. Nepal Millennium Development Goals Progress Report 2013. Kathmandu, Nepal: National Planning Commission, and United Nations Country Team Nepal; 2013.Google Scholar
  6. Suvedi BK, Pradhan P, Barnett S, Puri M, Rai Chitrakar S, Poudel P, et al. Nepal Maternal Mortality and Morbidity Study 2008/2009: Summary of Preliminary Findings. Kathmandu, Nepal: Family Health division, Department of Health Services, Ministry of Health, Government of Nepal; 2009.Google Scholar
  7. Karkee R, Lee AH, Khanal V, Pokharel PK, Binns CW. Obstetric complications and cesarean delivery in Nepal. Int J Gynecol Obstet. 2014;125:33–6.View ArticleGoogle Scholar
  8. Mesko N, Osrin D, Tamang S, Shrestha BP, Manandhar DS, Manandhar M, Standing H, Costello AM. Care for perinatal illness in rural Nepal: a descriptive study with cross-sectional and qualitative components. BMC Int Health Human Rights. 2003;3:3.View ArticleGoogle Scholar
  9. Mullan Z. Rebuilding Nepal. The Lancet Global health. 2015;3:e654.View ArticlePubMedGoogle Scholar
  10. Khanal V, Khanal P, Lee AH. Sustaining progress in maternal and child health in Nepal. Lancet. 2015;385:2573.View ArticlePubMedGoogle Scholar
  11. District Public Health Office Rupandehi. Annual Repport. Bhairahawa, Nepal: DPHO, Rupandehi; 2014.Google Scholar
  12. Central Burea of Statistics. National Population and Housing Census 2011. Kathmandu: CBS; 2012.Google Scholar
  13. Khanal V, Scott JA, Lee AH, Karkee R, Binns CW. Factors associated with early initiation of breastfeeding in Western Nepal. Int J Environ Res Public Health. 2015;12:9562–74.View ArticlePubMedPubMed CentralGoogle Scholar
  14. Khanal V, Lee AH, Karkee R, Binns CW. Prevalence and factors associated with prelacteal feeding in Western Nepal. Women Birth. 2015;29(1):12–7.View ArticlePubMedGoogle Scholar
  15. Ministry of Health and Population (MOHP) [Nepal], New ERA, ICF International Inc. Nepal Demographic and Health Survey 2011. Kathmandu,Nepal: Ministry of Health and Population, New ERA, and ICF International, Calverton, Maryland; 2012.Google Scholar
  16. Karkee R, Lee A, Khanal V, Binns C. A community-based prospective cohort study of exclusive breastfeeding in central Nepal. BMC Public Health. 2014;14:927.View ArticlePubMedPubMed CentralGoogle Scholar
  17. Stillbirths [http://www.who.int/maternal_child_adolescent/epidemiology/stillbirth/en/]. Accessed date: 25 April, 2015.
  18. Agho KE, Dibley MJ, Odiase JI, Ogbonmwan SM. Determinants of exclusive breastfeeding in Nigeria. BMC Pregnancy Childbirth. 2011;11:2.View ArticlePubMedPubMed CentralGoogle Scholar
  19. Maternal Health and Safe Motherhood Programme. Indicators to monitor maternal health goals: report of a technical working group, Geneva, 8–12 November 1993. Geneva: World Health Organization, Division of Family Health; 1994.Google Scholar
  20. Neuman M, Alcock G, Azad K, Kuddus A, Osrin D, More NS, Nair N, Tripathy P, Sikorski C, Saville N, et al. Prevalence and determinants of caesarean section in private and public health facilities in underserved South Asian communities: cross-sectional analysis of data from Bangladesh, India and Nepal. BMJ Open. 2014;4(12):e005982.View ArticlePubMedPubMed CentralGoogle Scholar
  21. Child Health Division, Family Health Division, Save the Children Nepal. A Synthesis of Recent Studies on Maternal and Newborn Survival Interventions in Nepal. Kathmandu: Nepal Child Health Division and Family Health Division, Ministry of Health and Population; 2014.Google Scholar
  22. Ministry of Health and Population (MOHP) [Nepal], New ERA, Macro International Inc: Nepal Demographic and Health Survey 2006. Kathmandu [Nepal]; 2007.Google Scholar
  23. Karkee R, Lee AH, Binns CW. Bypassing birth centres for childbirth: an analysis of data from a community-based prospective cohort study in Nepal. Health Policy Plan. 2013;30(1):1–7.View ArticlePubMedGoogle Scholar
  24. Manandhar S, Ojha A, Manandhar D, Shrestha B, Shrestha D, Saville N, Costello A, Osrin D. Causes of stillbirths and neonatal deaths in Dhanusha district, Nepal: a verbal autopsy study. KUMJ. 2010;8:62.PubMedPubMed CentralGoogle Scholar
  25. Shrestha SR, Yadav B. Risk factors associated with still births. J Nepal Med Assoc. 2010;49(177):84–7.Google Scholar
  26. Ministry of Health and Population, USAID, IRHDTC Nepal. A Report on Verbal Autopsy to Ascertain the Causes of Neonatal Deaths in Nepal. Kathmandu, Nepal: Ministry of Health and Population, USAID, IRHDTC Nepal; 2014.Google Scholar
  27. Bhutta ZA, Yakoob MY, Lawn JE, Rizvi A, Friberg IK, Weissman E, Buchmann E, Goldenberg RL. Stillbirths: what difference can we make and at what cost? Lancet. 2011;377:1523–38.View ArticlePubMedGoogle Scholar
  28. Family Health Division, New ERA, ICF International Inc., USAID. Results from Assessing Birthing Centers in Nepal. Kathmandu, Nepal: Family Health Division, New ERA & New ERA; 2014.Google Scholar
  29. Bang RA, Bang AT, Reddy MH, Deshmukh MD, Baitule SB, Filippi V. Maternal morbidity during labour and the puerperium in rural homes and the need for medical attention: A prospective observational study in Gadchiroli, India. BJOG. 2004;111:231–8.View ArticlePubMedGoogle Scholar
  30. Nepal earthquake: Women and girls in need [http://www.unfpa.org/resources/nepal-earthquake-women-and-girls-need]. Accessed date: 16 July 2015.
  31. Earthquake in Nepal: Statement by the Executive Director [http://www.unfpa.org/news/earthquake-nepal-statement-executive-director]. Accessed date: 16 July 2015.
  32. Devkota M, Shakya G, K.C. N, Dariang M, Upadhyay M, Karn S, Hulton L, Koblinsky M. Readiness of Comprehensive Obstetric and Neonatal Emergency Care in Nepal. Nepal National Health Sector Support Programme and Ministry of Health and Population of Nepal: Kathmandu; 2011.Google Scholar
  33. Ministry of Health and Population: Annual Report. Kathmandu; 2012/2013.Google Scholar
  34. Ministry of Health and Population, Gynuity, Era N. Evaluation of Postpartum Heaemorrhage Prevention Program in Nepal . Kathmandu, Nepal: Ministry of Health and Population, Gynuity, and New Era; 2014.Google Scholar
  35. Ashish K, Nelin V, Wrammert J, Ewald U, Vitrakoti R, Baral GN, Målqvist M. Risk factors for antepartum stillbirth: a case-control study in Nepal. BMC Pregnancy & Childbirth. 2015;15:1.Google Scholar

Copyright

© Khanal et al. 2016

Advertisement