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  1. Birth defects (BD) constitute an important public health issue as they are the main cause of infant death. Their prevalence in Europe for 2008–2012 was 25.6 per 1000 newborns. To date, there are no population-...

    Authors: Vitaly A Postoev, Evert Nieboer, Andrej M Grjibovski and Jon Øyvind Odland
    Citation: Reproductive Health 2015 12:3
  2. A growing number of middle-income countries are scaling up youth-friendly sexual and reproductive health pilot projects to national level programmes. Yet, there are few case studies on successful national leve...

    Authors: Jari Kempers, Evert Ketting, Venkatraman Chandra-Mouli and Triin Raudsepp
    Citation: Reproductive Health 2015 12:2
  3. In some developing countries a woman’s decision to utilize maternal health care services is not made by the woman herself but by other family members. The perception of family members regarding who is the most...

    Authors: Priti Upadhyay, Tippawan Liabsuetrakul, Amir Babu Shrestha and Neelam Pradhan
    Citation: Reproductive Health 2014 11:92
  4. The burden of maternal mortality in sub-Saharan Africa is very high. In Ghana maternal mortality ratio was 380 deaths per 100,000 live births in 2013. Skilled birth attendance has been shown to reduce maternal...

    Authors: Evelyn Sakeah, Lois McCloskey, Judith Bernstein, Kojo Yeboah-Antwi, Samuel Mills and Henry V Doctor
    Citation: Reproductive Health 2014 11:90
  5. The State of the World’s Midwifery Report 2014: A universal pathway, a women’s right to health (SoWMy2014) was published in June 2014 and joins the ranks of a number of publications which contribute to the gro...

    Authors: Frances Day-Stirk, Frances McConville, James Campbell, Laura Laski, Maria Guerra-Arias, Petra ten Hoope-Bender, Michaela Michel-Schuldt and Luc de Bernis
    Citation: Reproductive Health 2014 11:89
  6. Young people particularly women are at increased risk of undesirable sexual and reproductive health (SRH) outcomes. Structural factors have been reported as driving some of these risks. Although several interv...

    Authors: Joyce Wamoyi, Gerry Mshana, Aika Mongi, Nyasule Neke, Saidi Kapiga and John Changalucha
    Citation: Reproductive Health 2014 11:88
  7. Major improvements to Rwanda’s health system, infrastructure, and social programs over the last decade have led to a rapid fertility transition unique from other African countries. The total fertility rate fel...

    Authors: Vedaste Ndahindwa, Collins Kamanzi, Muhammed Semakula, François Abalikumwe, Bethany Hedt-Gauthier and Dana R Thomson
    Citation: Reproductive Health 2014 11:87
  8. Sexual behaviour and sexual practices affect the risk for acquisition and transmission of HIV infection. This study tries to identify differences in sexual behaviour (condom use with non-marital partners, mult...

    Authors: Morenike O Folayan, Morolake Odetoyinbo, Brandon Brown and Abigail Harrison
    Citation: Reproductive Health 2014 11:83
  9. The world has made enormous progress in improving child survival since 1990, reducing the under-five mortality rate by nearly half from 90 to 46 deaths per 1,000 live births in 2013. Currently, the global unde...

    Authors: Tessa Wardlaw, Danzhen You, Lucia Hug, Agbessi Amouzou and Holly Newby
    Citation: Reproductive Health 2014 11:82
  10. Antiretroviral treatment restores physical functioning and may have an impact on fertility desires. Counseling is given to HIV positive women to create awareness and to provide information on pregnancy and del...

    Authors: Jane Kabami, Eleanor Turyakira, Sam Biraro and Francis Bajunirwe
    Citation: Reproductive Health 2014 11:81
  11. Group B streptococcus (GBS) has been implicated in adverse pregnancy outcomes. GBS recto-vaginal colonization rates significantly vary among different communities and geographic locations. Limited data is avai...

    Authors: Zufan Lakew Woldu, Tatek Gebreegziabher Teklehaimanot, Sisay Teklu Waji and Mahlet Yigeremu Gebremariam
    Citation: Reproductive Health 2014 11:80
  12. Preterm birth is the main cause of morbidity and mortality during the perinatal period. Classical risk factors are held responsible for only 1/3 of preterm births and no current intervention has produced an ap...

    Authors: Antônio Augusto Moura da Silva, Vanda Maria Ferreira Simões, Marco Antonio Barbieri, Viviane Cunha Cardoso, Claudia Maria Coelho Alves, Erika Bárbara Abreu Fonseca Thomaz, Rejane Christine de Sousa Queiroz, Ricardo Carvalho Cavalli, Rosângela Fernandes Lucena Batista and Heloísa Bettiol
    Citation: Reproductive Health 2014 11:79
  13. Administration of exogenous progesterone for luteal phase support has become a standard of practice. Intramuscular (IM) injections of progesterone in oil (PIO) and vaginal administration of progesterone are th...

    Authors: Angeline N Beltsos, Mark D Sanchez, Kevin J Doody, Mark R Bush, Alice D Domar and Michael G Collins
    Citation: Reproductive Health 2014 11:78
  14. Sexual and reproductive health communications are most likely promoting healthy sexual development and reduce sexual risks. Communication is the principal means for parents to transmit sexual values, beliefs, ...

    Authors: Mulatuwa Ayalew, Bezatu Mengistie and Agumasie Semahegn
    Citation: Reproductive Health 2014 11:77
  15. Over the years, IVF/ICSI protocols have continued to evolve with efforts to improve outcomes. As a result, treatment success may be related to certain procedural factors, including number of embryos transferre...

    Authors: Alexa A Nardelli, Tania Stafinski, Tarek Motan, Kristin Klein and Devidas Menon
    Citation: Reproductive Health 2014 11:76
  16. Virtually all the evidence on the relationship between women’s empowerment and use of contraception comes from cross-sectional studies that have emphasized macrosocial factors.

    Authors: Federico R León, Rebecka Lundgren, Irit Sinai, Ragini Sinha and Victoria Jennings
    Citation: Reproductive Health 2014 11:74
  17. The preconception window has been recognized as one of the earliest sensitive windows of human development, and interventions that focus on this period have the potential to affect not only pregnancy but long ...

    Authors: Sunni L Mumford, Kara A Michels, Natasha Salaria, Pilar Valanzasca and José M Belizán
    Citation: Reproductive Health 2014 11:73
  18. There is a growing evidence base for preconception care - – the provision of biomedical, behavioral and social interventions to women and couples before conception occurs. Firstly, there is evidence that health p...

    Authors: Elizabeth Mason, Venkatraman Chandra-Mouli, Valentina Baltag, Charlotte Christiansen, Zohra S Lassi and Zulfiqar A Bhutta
    Citation: Reproductive Health 2014 11(Suppl 3):S8

    This article is part of a Supplement: Volume 11 Supplement 3

  19. The notion of preconception care aims to target the existing risks before pregnancy, whereby resources may be used to improve reproductive health and optimize knowledge before conceiving. The preconception per...

    Authors: Zohra S Lassi, Sohni V Dean, Dania Mallick and Zulfiqar A Bhutta
    Citation: Reproductive Health 2014 11(Suppl 3):S7

    This article is part of a Supplement: Volume 11 Supplement 3

  20. As providing health education, optimizing nutrition, and managing risk factors can be effective for ensuring a healthy outcome for women and her yet un-conceived baby, external influences play a significant ro...

    Authors: Zohra S Lassi, Ayesha M Imam, Sohni V Dean and Zulfiqar A Bhutta
    Citation: Reproductive Health 2014 11(Suppl 3):S6

    This article is part of a Supplement: Volume 11 Supplement 3

  21. A large proportion of women around the world suffer from chronic diseases including mental health diseases. In the United States alone, over 12% of women of reproductive age suffer from a chronic medical condi...

    Authors: Zohra S Lassi, Ayesha M Imam, Sohni V Dean and Zulfiqar A Bhutta
    Citation: Reproductive Health 2014 11(Suppl 3):S5

    This article is part of a Supplement: Volume 11 Supplement 3

  22. Infections can impact the reproductive health of women and hence may influence pregnancy related outcomes for both the mother and the child. These infections range from sexually transmitted infections (STIs) t...

    Authors: Zohra S Lassi, Ayesha M Imam, Sohni V Dean and Zulfiqar A Bhutta
    Citation: Reproductive Health 2014 11(Suppl 3):S4

    This article is part of a Supplement: Volume 11 Supplement 3

  23. There is increasingly a double burden of under-nutrition and obesity in women of reproductive age. Preconception underweight or overweight, short stature and micronutrient deficiencies all contribute to excess...

    Authors: Sohni V Dean, Zohra S Lassi, Ayesha M Imam and Zulfiqar A Bhutta
    Citation: Reproductive Health 2014 11(Suppl 3):S3

    This article is part of a Supplement: Volume 11 Supplement 3

  24. Preconception care recognizes that many adolescent girls and young women will be thrust into motherhood without the knowledge, skills or support they need. Sixty million adolescents give birth each year worldw...

    Authors: Sohni V Dean, Zohra S Lassi, Ayesha M Imam and Zulfiqar A Bhutta
    Citation: Reproductive Health 2014 11(Suppl 3):S2

    This article is part of a Supplement: Volume 11 Supplement 3

  25. Preconception care includes any intervention to optimize a woman’s health before pregnancy with the aim to improve maternal, newborn and child health (MNCH) outcomes. Preconception care bridges the gap in the ...

    Authors: Sohni V Dean, Zohra S Lassi, Ayesha M Imam and Zulfiqar A Bhutta
    Citation: Reproductive Health 2014 11(Suppl 3):S1

    This article is part of a Supplement: Volume 11 Supplement 3

  26. In Argentina, abortion has been decriminalized under certain circumstances since the enactment of the Penal Code in 1922. Nevertheless, access to abortion under this regulatory framework has been extremely lim...

    Authors: Silvina Ramos, Mariana Romero and Agustina Ramón Michel
    Citation: Reproductive Health 2014 11:72
  27. High-quality obstetric delivery in a health facility reduces maternal and perinatal morbidity and mortality. This systematic review synthesizes qualitative evidence related to the facilitators and barriers to ...

    Authors: Meghan A Bohren, Erin C Hunter, Heather M Munthe-Kaas, João Paulo Souza, Joshua P Vogel and A Metin Gülmezoglu
    Citation: Reproductive Health 2014 11:71
  28. Between 250,000-280,000 women die worldwide during pregnancy and childbirth each year and children in low- and middle-income countries are 56 times more likely to die before the age of 5 than children in high-...

    Authors: José M Belizán, Natasha Salaria, Pilar Valanzasca and Michael Mbizvo
    Citation: Reproductive Health 2014 11:69
  29. This series of papers focuses on a quality of care framework for maternal health, and systematically reviews the evidence of interventions aimed at improving care at the community-, district- and factility-lev...

    Authors: Zulfiqar A Bhutta, Rehana A Salam, Zohra S Lassi, Anne Austin and Ana Langer
    Citation: Reproductive Health 2014 11(Suppl 2):S5

    This article is part of a Supplement: Volume 11 Supplement 2

  30. Most of the maternal and newborn deaths occur at birth or within 24 hours of birth. Therefore, essential lifesaving interventions need to be delivered at basic or comprehensive emergency obstetric care facilit...

    Authors: Jai K Das, Rohail Kumar, Rehana A Salam, Zohra S Lassi and Zulfiqar A Bhutta
    Citation: Reproductive Health 2014 11(Suppl 2):S4

    This article is part of a Supplement: Volume 11 Supplement 2

  31. District level healthcare serves as a nexus between community and district level facilities. Inputs at the district level can be broadly divided into governance and accountability mechanisms; leadership and su...

    Authors: Rehana A Salam, Zohra S Lassi, Jai K Das and Zulfiqar A Bhutta
    Citation: Reproductive Health 2014 11(Suppl 2):S3

    This article is part of a Supplement: Volume 11 Supplement 2

  32. Annually around 40 million mothers give birth at home without any trained health worker. Consequently, most of the maternal and neonatal mortalities occur at the community level due to lack of good quality car...

    Authors: Zohra S Lassi, Jai K Das, Rehana A Salam and Zulfiqar A Bhutta
    Citation: Reproductive Health 2014 11(Suppl 2):S2

    This article is part of a Supplement: Volume 11 Supplement 2

  33. Despite progress in recent years, an estimated 273,500 women died as a result of maternal causes in 2010. The burden of these deaths is disproportionately bourne by women who reside in low income countries or ...

    Authors: Anne Austin, Ana Langer, Rehana A Salam, Zohra S Lassi, Jai K Das and Zulfiqar A Bhutta
    Citation: Reproductive Health 2014 11(Suppl 2):S1

    This article is part of a Supplement: Volume 11 Supplement 2

  34. In an effort to accelerate progress towards achieving Millennium Development Goal (MDG) 4 and 5, provision of essential reproductive, maternal, newborn and child health (RMNCH) interventions is being considere...

    Authors: Zohra S Lassi, Rohail Kumar, Tarab Mansoor, Rehana A Salam, Jai K Das and Zulfiqar A Bhutta
    Citation: Reproductive Health 2014 11(Suppl 1):S5

    This article is part of a Supplement: Volume 11 Supplement 1

  35. Child health is a growing concern at the global level, as infectious diseases and preventable conditions claim hundreds of lives of children under the age of five in low-income countries. Approximately 7.6 mil...

    Authors: Zohra S Lassi, Dania Mallick, Jai K Das, Lekho Mal, Rehana A Salam and Zulfiqar A Bhutta
    Citation: Reproductive Health 2014 11(Suppl 1):S4

    This article is part of a Supplement: Volume 11 Supplement 1

  36. Childbirth and the postnatal period, spanning from right after birth to the following several weeks, presents a time in which the number of deaths reported still remain alarmingly high. Worldwide, about 800 wo...

    Authors: Rehana A Salam, Tarab Mansoor, Dania Mallick, Zohra S Lassi, Jai K Das and Zulfiqar A Bhutta
    Citation: Reproductive Health 2014 11(Suppl 1):S3

    This article is part of a Supplement: Volume 11 Supplement 1

  37. The statistics related to pregnancy and its outcomes are staggering: annually, an estimated 250000-280000 women die during childbirth. Unfortunately, a large number of women receive little or no care during or...

    Authors: Zohra S Lassi, Tarab Mansoor, Rehana A Salam, Jai K Das and Zulfiqar A Bhutta
    Citation: Reproductive Health 2014 11(Suppl 1):S2

    This article is part of a Supplement: Volume 11 Supplement 1

  38. Worldwide, 250,000–280,000 women die during pregnancy and childbirth every year and an estimated 6.55 million children die under the age of five. The majority of maternal deaths occur during or immediately aft...

    Authors: Zohra S Lassi, Rehana A Salam, Jai K Das and Zulfiqar A Bhutta
    Citation: Reproductive Health 2014 11(Suppl 1):S1

    This article is part of a Supplement: Volume 11 Supplement 1

  39. Fragile X syndrome (FXS) and its associated disorders are caused by the expansion of the CGG repeat in the 5′ untranslated region of the fragile X mental retardation 1 gene (FMR1). The full mutation, defined as >...

    Authors: Emmanuel Peprah
    Citation: Reproductive Health 2014 11:67
  40. World Health Organization (WHO) recommends that the episiotomy rate should be around 10%, which is already a reality in many European countries. Currently the use of episiotomy should be restricted and physici...

    Authors: Inês Melo, Leila Katz, Isabela Coutinho and Melania Maria Amorim
    Citation: Reproductive Health 2014 11:66
  41. Average contraceptive prevalence rate in the Nkwanta district of Ghana was estimated to be 6.2% relative to the national average at the time, of 19%. While several efforts had been made to improve family plann...

    Authors: Sebastian Eliason, John K Awoonor-Williams, Cecilia Eliason, Jacob Novignon, Justice Nonvignon and Moses Aikins
    Citation: Reproductive Health 2014 11:65

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